SCHEMBL7040367

SCHEMBL7040367

CCC(C)(C)OC(=O)N1C(=O)C2=C(c3ccccc3)N(C(=O)OC(C)(C)CC)C(=O)C2=C1c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.35
RIPK1 Q13546 1/20 0.35
CYP2C19 P33261 3/20 0.33
KLK7 P49862 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2D6 P10635 1/20 0.33
HSP90AA1 P07900 2/20 0.32
HSP90AB1 P08238 2/20 0.32
HIF1A Q16665 1/20 0.32
CKS1B P61024 1/20 0.32
SKP1 P63208 1/20 0.32
SKP2 Q13309 1/20 0.32
KDM4E B2RXH2 1/20 0.31
RCE1 Q9Y256 1/20 0.31
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
KLK5 Q9Y337 1/20 0.31
CNR2 P34972 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
MAPT P10636 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2617069 0.86 CYP3A4 (0.36) CYP2C19CYP1A2CYP2D6HSP90AA1HSP90AB1
SCHEMBL902929 0.85 BCHE (0.48) BCHEKLK7CKS1BSKP1SKP2
SCHEMBL5699442 0.82 CNR2 (0.42) CYP1A2CNR2SLC16A3
SCHEMBL13461157 0.80 ALDH1A1 (0.32) CYP2C19CYP1A2CYP2D6HSP90AA1HSP90AB1
SCHEMBL7900611 0.78 BCHE (0.42) BCHEKLK7CKS1BSKP1SKP2
SCHEMBL14306561 0.78 ASAH1 (0.42) BCHEKDM4ESMN1; SMN2L3MBTL1NPC1
SCHEMBL13461004 0.75 ALDH1A1 (0.31) CYP1A2
SCHEMBL7796082 0.75 BCHE (0.52) BCHECNR2MAPTL3MBTL1LMNA
SCHEMBL12535685 0.75 CNR2 (0.39) CYP1A2CNR2SLC16A3
SCHEMBL14275474 0.74 BCHE (0.40) BCHEKLK7CKS1BSKP1SKP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0922737-B1 Ink-jet inks comprising pigment precursors HEWLETT PACKARD CO (US) 2003-03-26 EP disclosed
US-6102996-A Ink-jet inks comprising pigment precursors HEWLETT-PACKARD COMPANY (US) 2000-08-15 US disclosed
EP-0922737-A1 Ink-jet inks comprising pigment precursors Hewlett-Packard Company (US) 1999-06-16 EP disclosed