SCHEMBL902929

SCHEMBL902929

CC(C)(C)OC(=O)N1C(=O)C2=C(c3ccccc3)N(C(=O)OC(C)(C)C)C(=O)C2=C1c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.48
CKS1B P61024 2/20 0.39
SKP1 P63208 2/20 0.39
SKP2 Q13309 2/20 0.39
GPR119 Q8TDV5 1/20 0.39
KLK7 P49862 2/20 0.38
USP30 Q70CQ3 5/20 0.38
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ABCB1 P08183 1/20 0.36
DTYMK P23919 1/20 0.36
GRM6 O15303 1/20 0.36
KLK5 Q9Y337 1/20 0.36
NR1H2 P55055 2/20 0.35
RXRA P19793 1/20 0.35
NR1H3 Q13133 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7900611 0.92 BCHE (0.42) BCHECKS1BSKP1SKP2GPR119
SCHEMBL14275474 0.87 BCHE (0.40) BCHECKS1BSKP1SKP2GPR119
SCHEMBL24565414 0.86 BCHE (0.40) BCHEGPR119KLK7ALDH1A1DTYMK
SCHEMBL8949810 0.86 GPR119 (0.40) BCHEGPR119ALDH1A1HSD17B10NR1H2
SCHEMBL6321306 0.86 BCHE (0.39) BCHECKS1BSKP1SKP2GPR119
SCHEMBL7040367 0.85 BCHE (0.35) BCHECKS1BSKP1SKP2KLK7
SCHEMBL6322676 0.85 MEN1 (0.43) BCHE
SCHEMBL7946813 0.85 HSD11B1 (0.40) BCHETDP1DTYMK
SCHEMBL12393911 0.85 GPR119 (0.41) BCHEGPR119USP30
SCHEMBL8053167 0.84 GPR119 (0.42) BCHEGPR119USP30ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11246809-A None JP disclosed
EP-2621927-B1 SEMICONDUCTORS BASED ON DIKETOPYRROLOPYRROLES BASF SE (DE) 2020-02-12 EP disclosed
US-8946376-B2 Semiconductors based on diketopyrrolopyrroles BASF SE (DE) 2015-02-03 US disclosed
US-8946376-B2 Semiconductors based on diketopyrrolopyrroles BASF SE (DE) 2015-02-03 US disclosed
US-8283100-B2 Color forming compositions and associated methods HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2012-10-09 US disclosed
US-8177901-B2 Porous inorganic materials of silcon and oxygen BASF SE Ludwigshafen (DE) 2012-05-15 US disclosed
US-8177901-B2 Porous inorganic materials of silcon and oxygen BASF SE Ludwigshafen (DE) 2012-05-15 US disclosed
WO-2012041849-A1 SEMICONDUCTORS BASED ON DIKETOPYRROLOPYRROLES BASF SE (DE) 2012-04-05 WO disclosed
US-20120074393-A1 SEMICONDUCTORS BASED ON DIKETOPYRROLOPYRROLES BASF SE (DE) 2012-03-29 US disclosed
US-20120074393-A1 SEMICONDUCTORS BASED ON DIKETOPYRROLOPYRROLES BASF SE (DE) 2012-03-29 US disclosed
US-5821373-A WITH DIFFERENT 1,4-DIKETOPYRROLOPYRROLE OR QUINACRIDONE; PIGMENTING HIGH MOLECULAR WEIGHT MATERIALS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-10-13 US disclosed
WO-1998032800-A1 THIAZINE INDIGO PIGMENTS, SOLID SOLUTIONS THEREOF AND THEIR PREPARATION CLARIANT FINANCE (BVI) LIMITED (VG) 1998-07-30 WO disclosed
US-5756746-A KETOPYRROLES AND QUINACRIDONES FOR LIGHT STABLE AND WEATHER RESISTANT COLOR COMPOSITIONS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-05-26 US disclosed
US-5718998-A CONDUCTIVE SUBSTRATE; PHOTOSENSITIVE LAYER CONTAINING CHARGEGENERATING MATERIAL AND ORGANIC PIGMENT CIBA SPECIALTY CHEMICAL HOLDING, INC. (CH) 1998-02-17 US disclosed
EP-0765919-A2 Monophasic solid solutions with asymmetrical pyrrolo-(4-3-c)-pyrroles as host Ciba SC Holding AG (CH) 1997-04-02 EP disclosed
US-5616725-A REACTING PYRROLO(3,4-C)PYROLE DERIVATIVE WITH ONE OF COMPOUNDS SELECTED FROM DICARBONATES, TRIHALOACETATES, AZIDES, ALKYLIDENE-IMINOOXYFORMATE OR MIXTURES IN AN ORGANIC SOLVENT IN PRESENCE OF A BASIC CATALYST CIBA-GEIGY CORPORATION (US) 1997-04-01 US disclosed
EP-0763572-A2 Solid solutions of 1,4-diketopyrrolopyrroles Ciba SC Holding AG (CH) 1997-03-19 EP disclosed
EP-0718697-A2 Electrophotographic photoreceptor CIBA-GEIGY AG (CH) 1996-06-26 EP disclosed
US-5518539-A COLORFASTNESS FOR ORGANIC PIGMENT MIXTURES FOR SUBSTRATES CIBA-GEIGY CORPORATION (US) 1996-05-21 US disclosed
US-5484943-A FLUORESCENT PIGMENTS CIBA-GEIGY CORPORATION (US) 1996-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120074393-A1 SEMICONDUCTORS BASED ON DIKETOPYRROLOPYRROLES PDK1, CD2, DDT BCHE 3613/4885CKS1B 864/4885SKP1 218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.