SCHEMBL7900611

SCHEMBL7900611

CC(C)(C)OC(=O)N1C(=O)C2=C(c3ccc(C(C)(C)C)cc3)N(C(=O)OC(C)(C)C)C(=O)C2=C1c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.42
USP30 Q70CQ3 3/20 0.38
MAPT P10636 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HSD11B1 P28845 2/20 0.37
RORC P51449 1/20 0.36
DTYMK P23919 1/20 0.35
CKS1B P61024 1/20 0.35
SKP1 P63208 1/20 0.35
SKP2 Q13309 1/20 0.35
MAP3K5 Q99683 1/20 0.35
MEN1 O00255 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
DHODH Q02127 1/20 0.34
GPR119 Q8TDV5 1/20 0.34
KLK7 P49862 1/20 0.34
NPC1L1 Q9UHC9 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7946813 0.95 HSD11B1 (0.40) BCHEMAPTTDP1L3MBTL1HSD11B1
SCHEMBL902929 0.92 BCHE (0.48) BCHEUSP30TDP1DTYMKCKS1B
SCHEMBL24565414 0.82 BCHE (0.40) BCHEMAPTDTYMKGPR119KLK7
SCHEMBL8949810 0.82 GPR119 (0.40) BCHEMAPTMEN1KMT2ANPSR1
SCHEMBL6322676 0.81 MEN1 (0.43) BCHEMAPTMEN1KMT2ANPSR1
SCHEMBL14275474 0.80 BCHE (0.40) BCHEUSP30L3MBTL1DTYMKCKS1B
SCHEMBL6321306 0.79 BCHE (0.39) BCHEUSP30CKS1BSKP1SKP2
SCHEMBL7040367 0.78 BCHE (0.35) BCHEUSP30MAPTL3MBTL1CKS1B
SCHEMBL12393911 0.78 GPR119 (0.41) BCHEUSP30GPR119
SCHEMBL8053167 0.77 GPR119 (0.42) BCHEUSP30MAPTNPSR1GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6211347-B1 INKS, COLOR FILTERS CIBA SPECIALTY CHEMICALS CORPORATION 2001-04-03 US disclosed
US-6071989-A MIXING LATENT PIGMENT, POLYMER AND SOLVENT; REMOVING SOLVENT; SUBJECTING SOLVENT-FREE MIXTURE TO THERMAL, CHEMICAL OR PHOTOLYTIC TREATMENT; ADDING SOLVENT TO TREATED MIXTURE CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-06-06 US disclosed