Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | S100B | P04271 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7059521 | 0.95 | ALDH1A1 (0.35) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL7040510 | 0.90 | ALDH1A1 (0.33) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL7059525 | 0.85 | ALDH1A1 (0.33) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL7043243 | 0.84 | POLB (0.33) | S100B | |
| SCHEMBL6290903 | 0.79 | ALDH1A1 (0.44) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL7038341 | 0.78 | ALDH1A1 (0.33) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL7039034 | 0.74 | POLB (0.34) | S100B | |
| SCHEMBL7043247 | 0.73 | POLB (0.32) | — | |
| SCHEMBL6290905 | 0.72 | ALDH1A1 (0.38) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL7043572 | 0.72 | S100B (0.46) | S100B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030167579-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-09-11 | — | — | US | claimed |
| US-20030159221-A1 | Oxidation dyeing composition for keratinous fibres with a particular paraphenylene-diamine derivative and a particular direct dyeing agent | L'OREAL S.A. (FR) | 2003-08-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030159221-A1 | Oxidation dyeing composition for keratinous fibres with a particular paraphenylene-diamine derivative and a particular direct dyeing agent | KRT18, CDC73, DAO | ALDH1A1 383/4885CYP3A4 364/4885TSHR 4453/4885 |
| US-20030167579-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | KRT18, PPOX, COXFA4L2 | ALDH1A1 361/4885CYP3A4 577/4885TSHR 4776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.