Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.36 |
| ▸ | CA2 | P00918 | 6/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120451 | 0.91 | F2 (0.36) | CA1CA2F2ADAM17MEN1 | |
| SCHEMBL8112864 | 0.91 | F2 (0.36) | CA1CA2F2ADAM17MEN1 | |
| SCHEMBL8120928 | 0.90 | NR1D1 (0.36) | CA1CA2F2ADAM17GAA | |
| SCHEMBL8114819 | 0.90 | F2 (0.35) | CA1CA2F2ADAM17MEN1 | |
| SCHEMBL8126120 | 0.88 | CA12 (0.36) | CA1CA2F2ADAM17MEN1 | |
| SCHEMBL8112880 | 0.85 | CA1 (0.34) | CA1CA2F2 | |
| SCHEMBL8125342 | 0.84 | F2 (0.37) | CA1CA2F2ADAM17 | |
| SCHEMBL8115107 | 0.84 | F2 (0.33) | F2ADAM17 | |
| SCHEMBL8112706 | 0.84 | F2 (0.33) | F2ADAM17 | |
| SCHEMBL8528534 | 0.83 | NPY1R (0.38) | CA1CA2F2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | disclosed |