Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 2/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 5/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | ESRRB | O95718 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112864 | 0.91 | F2 (0.36) | F2ESRRGNPY1RCA2CA1 | |
| SCHEMBL7040748 | 0.84 | CA1 (0.36) | F2CA2CA1ADAM17 | |
| SCHEMBL8120451 | 0.84 | F2 (0.36) | F2CA2CA1ADAM17 | |
| SCHEMBL8120928 | 0.83 | NR1D1 (0.36) | F2CA2CA1ADAM17 | |
| SCHEMBL8114819 | 0.83 | F2 (0.35) | F2CA2CA1ADAM17 | |
| SCHEMBL8126120 | 0.81 | CA12 (0.36) | F2CA2CA1ADAM17 | |
| SCHEMBL8069642 | 0.80 | ESRRG (0.36) | ESRRG | |
| SCHEMBL8068255 | 0.80 | TPSAB1 (0.46) | SLC6A5 | |
| SCHEMBL8121207 | 0.80 | NPY1R (0.35) | F2NPY1RADAM17 | |
| SCHEMBL8112880 | 0.79 | CA1 (0.34) | F2CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |