Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CD74 | P04233 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16825864 | 0.83 | MAPT (0.76) | MAPTPOLBALDH1A1HPGDL3MBTL1 | |
| SCHEMBL27865005 | 0.75 | RAB9A (0.52) | MAPTPOLBALDH1A1HPGDL3MBTL1 | |
| Piperazine SCHEMBL28827893 | 0.74 | FLT3 (0.61) | MAPTPOLBALDH1A1HPGDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL27726072 | 0.74 | RAB9A (0.51) | MAPTPOLBALDH1A1HPGDL3MBTL1 | |
| SCHEMBL10498565 | 0.74 | FLT3 (0.65) | MAPTPOLBALDH1A1HPGDL3MBTL1 | |
| SCHEMBL31280218 | 0.74 | FLT3 (0.65) | MAPTPOLBALDH1A1HPGDL3MBTL1 | |
| SCHEMBL28325613 | 0.73 | MAPT (0.49) | MAPTPOLBALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL29794233 | 0.73 | HSD17B10 (0.78) | MAPTALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL29046357 | 0.73 | HSD17B10 (0.78) | MAPTALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL19284197 | 0.72 | ALDH1A1 (0.65) | MAPTPOLBALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194426-B1 | BENZOFURANE DERIVATIVES | MERCK PATENT GMBH (DE) | 2004-08-18 | — | — | EP | disclosed |