Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | ATP4A | P20648 | 2/20 | 0.43 |
| ▸ | ATP4B | P51164 | 2/20 | 0.43 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172198 | 0.83 | LTA4H (0.54) | ALDH1A1RAB9AL3MBTL1MEN1KMT2A | |
| Bromide SCHEMBL6832827 | 0.81 | RAB9A (0.56) | ALDH1A1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL7035076 | 0.80 | ALDH1A1 (0.58) | ALDH1A1RAB9AMEN1KMT2AGAA | |
| SCHEMBL16217968 | 0.79 | RAB9A (0.65) | LOXL2TAAR1ALDH1A1RAB9AL3MBTL1 | |
| Bromide SCHEMBL6830057 | 0.78 | ALDH1A1 (0.57) | ALDH1A1RAB9AMEN1KMT2AGAA | |
| SCHEMBL7038615 | 0.77 | MEN1 (0.46) | LOXL2TAAR1ALDH1A1RAB9AMEN1 | |
| SCHEMBL19625329 | 0.76 | NPC1 (0.43) | ALDH1A1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL7041676 | 0.76 | NPC1 (0.60) | ALDH1A1RAB9AMEN1KMT2AGAA | |
| SCHEMBL13341093 | 0.76 | NPC1 (0.43) | ALDH1A1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL21812776 | 0.76 | RAB9A (0.66) | LOXL2TAAR1ALDH1A1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030158199-A1 | Novel compounds for inhibition of Tie-2 | KYLIX, B.V. (NL) | 2003-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158199-A1 | Novel compounds for inhibition of Tie-2 | TIE1, TEK, KDR | LOXL2 220/4885TAAR1 2505/4885ALDH1A1 1890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.