Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.63 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3450460 | 0.85 | EPHX2 (0.52) | KEAP1MAPK1SMN1; SMN2EPHX2ALDH1A1 | |
| Phenylbutanoic Acid SCHEMBL10636202 | 0.83 | HDAC3 (0.64) | KEAP1FFAR1MAPK1SMN1; SMN2HDAC3 | |
| SCHEMBL7042959 | 0.83 | KLK7 (0.52) | KEAP1MAPK1SMN1; SMN2EPHX2ALDH1A1 | |
| Benzoic Acid SCHEMBL5787919 | 0.81 | KMT2A (0.50) | SMN1; SMN2ALDH1A1CYP2C19LMNAMAPT | |
| SCHEMBL2800 | 0.80 | HPGD (0.52) | ALDH1A1LMNAHTTNPSR1 | |
| Phenyl Propionic Acid SCHEMBL27523271 | 0.80 | KEAP1 (1.00) | KEAP1FFAR1FFAR4MAPK1SMN1; SMN2 | |
| Phenyl Propionic Acid SCHEMBL3419 | 0.80 | KEAP1 (1.00) | KEAP1FFAR1FFAR4MAPK1SMN1; SMN2 | |
| Phenyl Propionic Acid SCHEMBL29619843 | 0.80 | KEAP1 (1.00) | KEAP1FFAR1FFAR4MAPK1SMN1; SMN2 | |
| Phenyl Propionic Acid SCHEMBL13618844 | 0.80 | KEAP1 (1.00) | KEAP1FFAR1FFAR4MAPK1SMN1; SMN2 | |
| Phenyl Propionic Acid SCHEMBL235064 | 0.80 | KEAP1 (1.00) | KEAP1FFAR1FFAR4MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401801-A4 | SELECTIVE ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF | UNIV TENNESSEE RES CORP (US) | 2004-08-18 | — | — | EP | disclosed |
| EP-1401801-A1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF | THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002016310-A1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF | THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) | 2002-02-28 | — | — | WO | disclosed |