Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 1.00 |
| ▸ | FFAR1 | O14842 | 13/20 | 0.91 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.74 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.74 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.74 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.74 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.74 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.74 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.74 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.74 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.74 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.68 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenyl Propionic Acid SCHEMBL3419 | 1.00 | KEAP1 (1.00) | KEAP1FFAR1HDAC2HDAC8HDAC6 | |
| Phenyl Propionic Acid SCHEMBL27523271 | 1.00 | KEAP1 (1.00) | KEAP1FFAR1HDAC2HDAC8HDAC6 | |
| Phenyl Propionic Acid SCHEMBL13618844 | 1.00 | KEAP1 (1.00) | KEAP1FFAR1HDAC2HDAC8HDAC6 | |
| Phenyl Propionic Acid SCHEMBL29619843 | 1.00 | KEAP1 (1.00) | KEAP1FFAR1HDAC2HDAC8HDAC6 | |
| Phenyl Propionic Acid SCHEMBL10878208 | 0.97 | KEAP1 (0.95) | KEAP1FFAR1HDAC2HDAC8HDAC6 | |
| Phenyl Propionic Acid SCHEMBL8901632 | 0.97 | KEAP1 (0.95) | KEAP1FFAR1HDAC2HDAC8HDAC6 | |
| Phenyl Propionic Acid SCHEMBL3478262 | 0.97 | KEAP1 (0.95) | KEAP1FFAR1HDAC2HDAC8HDAC6 | |
| Phenyl Propionic Acid SCHEMBL9122761 | 0.97 | KEAP1 (0.95) | KEAP1FFAR1HDAC2HDAC8HDAC6 | |
| Phenyl Propionic Acid SCHEMBL2067973 | 0.97 | KEAP1 (0.95) | KEAP1FFAR1HDAC2HDAC8HDAC6 | |
| Phenyl Propionic Acid SCHEMBL2468015 | 0.97 | KEAP1 (0.95) | KEAP1FFAR1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023199324-A1 | MIXTURE OF 3-HEXENYL ESTER ISOMERS AND USES THEREOF | AGAN AROMA & FINE CHEMICALS LTD. (IL) | 2023-10-19 | — | — | WO | claimed |
| EP-3087969-B1 | PROTEASOME INHIBITORS AND USES THEREOF | ARBISER JACK L (US) | 2021-06-30 | — | — | EP | claimed |
| CN-109438238-B | Synthetic method of dihydrocinnamate compound | 陕西师范大学 | 2021-04-13 | — | — | CN | claimed |
| US-20180325854-A1 | USE OF PROTEASOME INHIBITORS TO TREAT OCULAR DISORDERS | ACCUITIS PHARMACEUTICALS INC (US) | 2018-11-15 | — | — | US | claimed |
| EP-3370709-A1 | USE OF PROTEASOME INHIBITORS TO TREAT OCULAR DISORDERS | Accuitis Pharmaceuticals, Inc. (US) | 2018-09-12 | — | — | EP | claimed |
| EP-2951313-B1 | BIOMARKERS RELATED TO INSULIN RESISTANCE PROGRESSION AND METHODS USING THE SAME | METABOLON INC (US) | 2018-03-07 | — | — | EP | claimed |
| WO-2017078953-A1 | USE OF PROTEASOME INHIBITORS TO TREAT OCULAR DISORDERS | ACCUITIS PHARMACEUTICALS, INC. (US) | 2017-05-11 | — | — | WO | claimed |
| EP-3087969-A1 | PROTEASOME INHIBITORS AND USES THEREOF | Arbiser, Jack L. (US) | 2016-11-02 | — | — | EP | claimed |
| US-8809283-B2 | Proteasome inhibitors and uses thereof | NATUDERM, LLC (US) | 2014-08-19 | — | — | US | claimed |
| EP-1895971-A2 | PROTEASOME INHIBITORS AND USES THEREOF | Arbiser, Jack (US) | 2008-03-12 | — | — | EP | claimed |
| US-20070004647-A1 | Proteasome inhibitors and uses thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-01-04 | — | — | US | claimed |
| WO-2006127525-A2 | PROTEASOME INHIBITORS AND USES THEREOF | ARBISER JACK (US) | 2006-11-30 | — | — | WO | claimed |
| US-20060167045-A1 | Combination therapy using a dual ppar alpha/gamma agonist and an angiotensin II type I receptor antagonist | MERCK & CO., INC. | 2006-07-27 | — | — | US | claimed |
| EP-1545540-A2 | COMBINATION THERAPY USING A DUAL PPAR ALPHA/GAMMA AGONIST AND AN ANGIOTENSIN II TYPE I RECEPTOR ANTAGONIST | Merck & Co., Inc. (US) | 2005-06-29 | — | — | EP | claimed |
| WO-2004017896-A2 | COMBINATION THERAPY USING A DUAL PPAR ALPHA/GAMMA AGONIST AND AN ANGIOTENSIN II TYPE I RECEPTOR ANTAGONIST | MERCK & CO., INC. (US) | 2004-03-04 | — | — | WO | claimed |
| EP-3710462-B1 | BRARTEMICIN ANALOGUES | VICTORIA LINK LTD (NZ) | 2026-05-13 | — | — | EP | disclosed |
| US-20250004378-A1 | Pattern Forming Method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2025-01-02 | — | — | US | disclosed |
| US-4558130-A | FLUORESCENCE ON OXIDATION BY HYDROGEN PEROXIDE; PEROXIDASE DETERMINATION | MILES LABORATORIES, INC. (US) | 1985-12-10 | — | — | US | disclosed |
| EP-0156261-A2 | Fluorogenic dihydroquinolone and dihydrocoumarin indicators for hydrogen peroxide | MILES INC. (US) | 1985-10-02 | — | — | EP | disclosed |
| EP-0121743-A2 | Optical indicator chalcogen compounds and use | MILES LABORATORIES, INC. (US) | 1984-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167045-A1 | Combination therapy using a dual ppar alpha/gamma agonist and an angiotensin II type I receptor antagonist | AGTR2, AGTR1, PPARA | KEAP1 2058/4885FFAR1 15/4885HDAC2 665/4885 |
| US-20070004647-A1 | Proteasome inhibitors and uses thereof | PSMB5, PSMB1, PSMA5 | KEAP1 67/4885FFAR1 4104/4885HDAC2 489/4885 |
| US-20180325854-A1 | USE OF PROTEASOME INHIBITORS TO TREAT OCULAR DISORDERS | PSMC1, PSMB1, PSMG3 | KEAP1 42/4885FFAR1 1959/4885HDAC2 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.