Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10636211 | 0.84 | EPHX2 (0.53) | KLK7TDP1EPHX2SMN1; SMN2MAPK1 | |
| Phenyl Propionic Acid SCHEMBL7042956 | 0.83 | KEAP1 (0.63) | EPHX2ALDH1A1L3MBTL1CYP2C19SMN1; SMN2 | |
| SCHEMBL1739439 | 0.82 | TDP1 (0.73) | TDP1ALDH1A1L3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL3450460 | 0.81 | EPHX2 (0.52) | KLK7TDP1EPHX2ALDH1A1L3MBTL1 | |
| SCHEMBL16417273 | 0.80 | KLK7 (0.51) | KLK7TDP1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9265342 | 0.80 | KLK7 (0.60) | KLK7TDP1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL5787921 | 0.80 | KLK7 (0.53) | KLK7TDP1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11843186 | 0.80 | HPGD (0.48) | KLK7TDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4065004 | 0.79 | KLK7 (0.59) | KLK7TDP1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL10557471 | 0.78 | HPGD (0.52) | KLK7TDP1ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401801-A4 | SELECTIVE ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF | UNIV TENNESSEE RES CORP (US) | 2004-08-18 | — | — | EP | disclosed |
| EP-1401801-A1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF | THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002016310-A1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF | THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) | 2002-02-28 | — | — | WO | disclosed |