Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065004 | 0.98 | KLK7 (0.59) | KLK7L3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL7495579 | 0.97 | KLK7 (0.57) | KLK7L3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL2232191 | 0.94 | ALDH1A1 (0.56) | KLK7L3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL29307410 | 0.88 | ALDH1A1 (0.50) | KLK7L3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL16417273 | 0.87 | KLK7 (0.51) | KLK7L3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL7060349 | 0.87 | ITGB3 (0.49) | KLK7L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL11832289 | 0.85 | ALDH1A1 (0.48) | KLK7L3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL305021 | 0.84 | ALDH1A1 (0.56) | L3MBTL1TDP1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL20023110 | 0.84 | MEN1 (0.50) | KLK7TDP1ALDH1A1MAPK1LMNA | |
| SCHEMBL31061934 | 0.83 | ALDH1A1 (0.49) | KLK7L3MBTL1ALDH1A1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641327-A1 | NOVEL ALPHA-MANNOSIDASE INHIBITORS | MERRELL PHARMACEUTICALS INC. (US) | 1995-03-08 | — | — | EP | disclosed |
| WO-1993005781-A1 | NOVEL ALPHA-MANNOSIDASE INHIBITORS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-04-01 | — | — | WO | disclosed |