SCHEMBL7043025

SCHEMBL7043025

CCCCOc1nn(-c2ccc(OC(F)(F)F)cc2)c(=O)o1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ABHD16A O95870 1/20 0.47
MGLL Q99685 2/20 0.46
FAAH O00519 1/20 0.46
LIPE Q05469 2/20 0.42
BCHE P06276 1/20 0.42
LIPC P11150 1/20 0.42
ACHE P22303 1/20 0.42
ALDH1A1 P00352 1/20 0.42
NPBWR1 P48145 2/20 0.40
MCHR1 Q99705 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
POLB P06746 1/20 0.40
TRPA1 O75762 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2701930 0.96 ABHD16A (0.44) ABHD16AMGLLFAAHLIPEBCHE
SCHEMBL2701417 0.96 ABHD16A (0.44) ABHD16AMGLLFAAHLIPEBCHE
SCHEMBL2703657 0.96 ABHD16A (0.44) ABHD16AMGLLFAAHLIPEBCHE
SCHEMBL2701842 0.96 ABHD16A (0.44) ABHD16AMGLLFAAHLIPEBCHE
SCHEMBL2701728 0.96 ABHD16A (0.44) ABHD16AMGLLFAAHLIPEBCHE
SCHEMBL2703021 0.96 ABHD16A (0.44) ABHD16AMGLLFAAHLIPEBCHE
SCHEMBL2702375 0.96 ABHD16A (0.44) ABHD16AMGLLFAAHLIPEBCHE
SCHEMBL2701809 0.94 ABHD16A (0.43) ABHD16AMGLLFAAHLIPEBCHE
SCHEMBL2702751 0.92 ABHD16A (0.40) ABHD16AMGLLFAAHLIPEBCHE
SCHEMBL2702352 0.92 ABHD16A (0.40) ABHD16AMGLLFAAHLIPEBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030236288-A1 Use of substituted 3-phenyl-5-alkoxy-3H-(1,3,4)-oxadizol-2-ones for inhibiting pancreatic lipase AVENTIS PHARMA DEUTSCHLAND GMBH 2003-12-25 US claimed
US-20030236288-A1 Use of substituted 3-phenyl-5-alkoxy-3H-(1,3,4)-oxadizol-2-ones for inhibiting pancreatic lipase AVENTIS PHARMA DEUTSCHLAND GMBH 2003-12-25 US disclosed
US-6596742-B1 Inhibitory effect on the hormone-sensitive lipase, HSL. insecticides, controlling metabolism and multistage synthesis AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2003-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030236288-A1 Use of substituted 3-phenyl-5-alkoxy-3H-(1,3,4)-oxadizol-2-ones for inhibiting pancreatic lipase PNLIP, CEL, LIPE ABHD16A 62/4885MGLL 10/4885FAAH 142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.