Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 11/20 | 0.72 |
| ▸ | MMP8 | P22894 | 5/20 | 0.72 |
| ▸ | MMP9 | P14780 | 14/20 | 0.59 |
| ▸ | MMP2 | P08253 | 7/20 | 0.59 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 9/20 | 0.52 |
| ▸ | MMP3 | P08254 | 3/20 | 0.52 |
| ▸ | MMP7 | P09237 | 3/20 | 0.52 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.49 |
| ▸ | BMP1 | P13497 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046221 | 0.90 | MMP13 (0.58) | MMP13MMP8MMP9MMP2MMP1 | |
| SCHEMBL6293833 | 0.84 | MMP13 (1.00) | MMP13MMP8MMP9MMP2ADAMTS4 | |
| SCHEMBL6294163 | 0.81 | MMP13 (0.62) | MMP13MMP8MMP9MMP2MMP1 | |
| SCHEMBL7045752 | 0.80 | MMP13 (0.71) | MMP13MMP8MMP9MMP2MMP1 | |
| SCHEMBL7342446 | 0.79 | MMP9 (0.66) | MMP13MMP8MMP9MMP2MMP1 | |
| SCHEMBL7342443 | 0.79 | MMP9 (0.66) | MMP13MMP8MMP9MMP2MMP1 | |
| SCHEMBL7077456 | 0.79 | MMP13 (0.54) | MMP13MMP8MMP9MMP2MMP1 | |
| Hydrochloric Acid SCHEMBL7350103 | 0.79 | MMP9 (0.65) | MMP13MMP8MMP9MMP2MMP1 | |
| Hydrochloric Acid SCHEMBL7350105 | 0.79 | MMP9 (0.65) | MMP13MMP8MMP9MMP2MMP1 | |
| Hydrochloric Acid SCHEMBL7413637 | 0.78 | MMP9 (0.64) | MMP13MMP8MMP9MMP2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030139414-A1 | Heterocyclic side chain containing, n-substituted metalloprotease inhibitors | THE PROCTER & GAMBLE COMPANY | 2003-07-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139414-A1 | Heterocyclic side chain containing, n-substituted metalloprotease inhibitors | MME, MMP2, MMP9 | MMP13 38/4885MMP8 37/4885MMP9 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.