Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28459975 | 0.90 | MAOA (0.36) | MEN1KMT2APOLBMAOAMAOB | |
| SCHEMBL231069 | 0.83 | — | — | |
| SCHEMBL17693335 | 0.78 | MEN1 (0.39) | MEN1KMT2APOLBMAOAMAOB | |
| SCHEMBL24278597 | 0.73 | MAOA (0.44) | MEN1KMT2APOLBMAOAMAOB | |
| SCHEMBL25796301 | 0.73 | MAOA (0.44) | MEN1KMT2APOLBMAOAMAOB | |
| SCHEMBL27053480 | 0.73 | MAOA (0.44) | MEN1KMT2APOLBMAOAMAOB | |
| SCHEMBL19911231 | 0.71 | MEN1 (0.35) | MEN1KMT2APOLBMAOAMAOB | |
| SCHEMBL21312230 | 0.71 | MEN1 (0.35) | MEN1KMT2APOLBMAOAMAOB | |
| SCHEMBL8760521 | 0.71 | MAOA (0.42) | MEN1KMT2AMAOAMAOBGAA | |
| SCHEMBL8028760 | 0.69 | KDM1A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003018521-A1 | SUBSTITUTED ALKENE DIOLS | ISIS INNOVATION LIMITED (GB) | 2003-03-06 | — | — | WO | disclosed |