SCHEMBL25796301

SCHEMBL25796301

OC1C2OC(c3ccccc32)C1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
POLB P06746 1/20 0.36
GAA P10253 1/20 0.35
ALDH1A1 P00352 1/20 0.32
ATM Q13315 1/20 0.32
SLC5A2 P31639 4/20 0.32
PTPN1 P18031 1/20 0.31
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
HDAC3 O15379 1/20 0.30
HDAC4 P56524 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC7 Q8WUI4 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC10 Q969S8 1/20 0.30
HDAC11 Q96DB2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24278597 1.00 MAOA (0.44) MAOAMAOBMEN1KMT2APOLB
SCHEMBL27053480 1.00 MAOA (0.44) MAOAMAOBMEN1KMT2APOLB
SCHEMBL231069 0.81
SCHEMBL17693335 0.75 MEN1 (0.39) MAOAMAOBMEN1KMT2APOLB
SCHEMBL7043281 0.73 MEN1 (0.38) MAOAMAOBMEN1KMT2APOLB
SCHEMBL2587972 0.73 MAOA (0.46) MAOAMAOBMEN1KMT2APOLB
SCHEMBL14028182 0.69 EDNRA (0.42) MAOAMAOBMEN1KMT2APOLB
SCHEMBL11298936 0.69 EDNRA (0.42) MAOAMAOBMEN1KMT2APOLB
SCHEMBL28459975 0.69 MAOA (0.36) MAOAMAOBMEN1KMT2APOLB
SCHEMBL27053510 0.69 EDNRA (0.42) MAOAMAOBMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4206182-A1 ESTER COMPOUND Mitsui Chemicals, Inc. (JP) 2023-07-05 EP disclosed