Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MPO | P05164 | 4/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7111070 | 0.99 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MPOBCHEACHE | |
| SCHEMBL22275069 | 0.89 | MPO (0.55) | ALDH1A1SMN1; SMN2MPOBCHEACHE | |
| SCHEMBL7113161 | 0.89 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MPOBCHEACHE | |
| SCHEMBL6836202 | 0.79 | GRIN2B (0.51) | ALDH1A1SMN1; SMN2GRIN2BTAAR1SPHK1 | |
| SCHEMBL6836169 | 0.79 | GRIN2B (0.51) | ALDH1A1SMN1; SMN2GRIN2BTAAR1SPHK1 | |
| SCHEMBL5691767 | 0.77 | GRIN2B (0.55) | GRIN2BTAAR1SPHK1OPRL1 | |
| SCHEMBL5689744 | 0.77 | GRIN2B (0.55) | GRIN2BTAAR1SPHK1OPRL1 | |
| SCHEMBL5689748 | 0.77 | GRIN2B (0.55) | GRIN2BTAAR1SPHK1OPRL1 | |
| SCHEMBL19363864 | 0.74 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2GRIN2BSPHK1LIPG | |
| SCHEMBL7979601 | 0.74 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MPOL3MBTL1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296934-A1 | CYCLOHEXYLAMINE DERIVATIVES AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2003-04-02 | — | — | EP | disclosed |
| WO-2001092204-A1 | CYCLOHEXYLAMINE DERIVATIVES AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2001-12-06 | — | — | WO | disclosed |