Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7047198 | 0.87 | MEN1 (0.40) | MEN1KMT2ACA1CA2CA7 | |
| SCHEMBL7047140 | 0.81 | ALDH1A1 (0.49) | EGFRALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL7044988 | 0.78 | KMT2A (0.34) | MEN1KMT2AEGFRALDH1A1MAPT | |
| SCHEMBL7051094 | 0.78 | CA1 (0.39) | MEN1KMT2ACA1CA2CA7 | |
| SCHEMBL7047320 | 0.78 | CA1 (0.39) | MEN1KMT2ACA1CA2CA7 | |
| SCHEMBL7049982 | 0.74 | MAOA (0.49) | ALDH1A1KDM4ERAB9A | |
| SCHEMBL7051549 | 0.73 | MAPT (0.61) | MEN1KMT2ACA1CA2CA7 | |
| SCHEMBL806906 | 0.73 | MAPT (0.38) | MEN1KMT2AEGFRPIM1ALDH1A1 | |
| SCHEMBL29444282 | 0.73 | MAPT (0.38) | MEN1KMT2AEGFRPIM1ALDH1A1 | |
| SCHEMBL7050811 | 0.72 | TDP2 (0.42) | MEN1KMT2AEGFRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300132-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | claimed |
| EP-1300132-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | disclosed |