SCHEMBL70440

SCHEMBL70440

COC(=O)c1ccc(-c2ccccc2)cc1C(=O)OC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 2/20 0.59
EGFR P00533 1/20 0.55
SLC6A3 Q01959 6/20 0.51
SLC6A4 P31645 4/20 0.51
MEN1 O00255 2/20 0.51
MAPT P10636 2/20 0.51
KMT2A Q03164 2/20 0.51
SLC6A2 P23975 2/20 0.51
ALDH1A1 P00352 1/20 0.51
GAA P10253 1/20 0.51
HPGD P15428 1/20 0.51
ACMSD Q8TDX5 3/20 0.50
HNF4A P41235 2/20 0.50
LMNA P02545 2/20 0.50
DHFR P00374 1/20 0.50
MCL1 Q07820 1/20 0.50
KDM4E B2RXH2 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
AXL P30530 1/20 0.49
TSHR P16473 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14252250 1.00 NR4A2 (0.59) NR4A2EGFRSLC6A3SLC6A4MEN1
SCHEMBL27552364 0.93 NR4A2 (0.56) NR4A2EGFRSLC6A3SLC6A4MEN1
SCHEMBL9813479 0.92 CA12 (0.52) NR4A2EGFRSLC6A3SLC6A4MAPT
SCHEMBL27780324 0.91 NR4A2 (0.55) NR4A2EGFRSLC6A3SLC6A4MEN1
SCHEMBL9813482 0.91 NR4A2 (0.49) NR4A2EGFRSLC6A3SLC6A4MEN1
SCHEMBL6466451 0.90 CA12 (0.53) NR4A2SLC6A3SLC6A4MAPTSLC6A2
SCHEMBL29733451 0.90 CA12 (0.53) NR4A2SLC6A3SLC6A4MAPTSLC6A2
Dimethyl Phthalate SCHEMBL3686830 0.86 TSHR (0.63) NR4A2SLC6A3SLC6A4MEN1MAPT
SCHEMBL7671667 0.86 NR4A2 (0.56) NR4A2EGFRSLC6A3SLC6A4MEN1
SCHEMBL21681991 0.86 ACMSD (0.66) NR4A2EGFRMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9394226-B2 3,4-dialkylbiphenyldicarboxylic acid compound, 3,4-dicarboalkoxybiphenyl-3′,4′-dicarboxylic acid and corresponding acid anhydrides, and processes for producing these compounds UBE INDUSTRIES, LTD. (JP) 2016-07-19 US disclosed
US-20150025263-A1 3,4-DIALKYLBIPHENYLDICARBOXYLIC ACID COMPOUND, 3,4-DICARBOALKOXYBIPHENYL-3',4'-DICARBOXYLIC ACID AND CORRESPONDING ACID ANHYDRIDES, AND PROCESSES FOR PRODUCING THESE COMPOUNDS UBE CORPORATION (JP) 2015-01-22 US disclosed
US-8859801-B2 3,4-dialkylbiphenyldicarboxylic acid compound, 3,4-dicarboalkoxybiphenyl-3', 4'-dicarboxylic acid and corresponding acid anhydrides, and processes for producing these compounds UBE INDUSTRIES, LTD. (JP) 2014-10-14 US disclosed
US-20130197261-A1 3,4-DIALKYLBIPHENYLDICARBOXYLIC ACID COMPOUND, 3,4-DICARBOALKOXYBIPHENYL-3', 4'-DICARBOXYLIC ACID AND CORRESPONDING ACID ANHYDRIDES, AND PROCESSES FOR PRODUCING THESE COMPOUNDS UBE INDUSTRIES, LTD. (JP) 2013-08-01 US disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-7339071-B2 Aryl ethynyl phthalic acid derivative and method for producing the same FUJIFILM CORPORATION (JP) 2008-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130197261-A1 3,4-DIALKYLBIPHENYLDICARBOXYLIC ACID COMPOUND, 3,4-DICARBOALKOXYBIPHENYL-3', 4'-DICARBOXYLIC ACID AND CORRESPONDING ACID ANHYDRIDES, AND PROCESSES FOR PRODUCING THESE COMPOUNDS CA4, CA2, CA1 NR4A2 642/4885EGFR 455/4885SLC6A3 2448/4885
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 NR4A2 581/4885EGFR 2651/4885SLC6A3 3908/4885
US-20150025263-A1 3,4-DIALKYLBIPHENYLDICARBOXYLIC ACID COMPOUND, 3,4-DICARBOALKOXYBIPHENYL-3',4'-DICARBOXYLIC ACID AND CORRESPONDING ACID ANHYDRIDES, AND PROCESSES FOR PRODUCING THESE COMPOUNDS CA4, CA1, CA2 NR4A2 621/4885EGFR 487/4885SLC6A3 2937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.