SCHEMBL9813482

SCHEMBL9813482

COC(=O)c1ccc(-c2cccc(-c3ccc(C(=O)OC)c(C(=O)OC)c3)c2)cc1C(=O)OC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 2/20 0.49
GAA P10253 3/20 0.49
ALDH1A1 P00352 3/20 0.49
MAPT P10636 2/20 0.49
HPGD P15428 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
CA12 O43570 3/20 0.47
CA1 P00915 3/20 0.47
CA2 P00918 3/20 0.47
CA9 Q16790 3/20 0.47
CA7 P43166 2/20 0.47
CA14 Q9ULX7 2/20 0.47
PDK2 Q15119 1/20 0.47
PDK4 Q16654 1/20 0.47
SLC6A3 Q01959 4/20 0.46
SLC6A4 P31645 3/20 0.46
SLC6A2 P23975 1/20 0.46
LMNA P02545 1/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6466451 0.92 CA12 (0.53) NR4A2GAAALDH1A1MAPTHPGD
SCHEMBL29733451 0.92 CA12 (0.53) NR4A2GAAALDH1A1MAPTHPGD
SCHEMBL70440 0.91 NR4A2 (0.59) NR4A2GAAALDH1A1MAPTHPGD
SCHEMBL14252250 0.91 NR4A2 (0.59) NR4A2GAAALDH1A1MAPTHPGD
SCHEMBL9813479 0.90 CA12 (0.52) NR4A2GAAALDH1A1MAPTHPGD
SCHEMBL6438400 0.88 GAA (0.54) NR4A2GAAALDH1A1MAPTHPGD
SCHEMBL27552364 0.84 NR4A2 (0.56) NR4A2GAAALDH1A1MAPTHPGD
SCHEMBL6516527 0.83 CFD (0.47) NR4A2GAAALDH1A1MAPTHPGD
SCHEMBL1709647 0.83 CFD (0.47) NR4A2GAAALDH1A1MAPTHPGD
SCHEMBL6433721 0.83 SLC6A4 (0.57) GAAALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0247731-B1 NOVEL PARA- OR META-TERPHENYLTETRACARBOXYLIC ACID, DIANHYDRIDE THEREOF AND PROCESS FOR PREPARING THE SAME Hitachi Chemical Co., Ltd. (JP) 1991-08-21 EP disclosed
US-4912233-A Para- or meta-terphenyltetracarboxylic acid, dianhydride thereof and process for preparing the same HITACHI CHEMICAL COMPANY, LTD. (JP) 1990-03-27 US disclosed
EP-0247731-A1 Novel para- or meta-terphenyltetracarboxylic acid, dianhydride thereof and process for preparing the same Hitachi Chemical Co., Ltd. (JP) 1987-12-02 EP disclosed