Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | GLA | P06280 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.56 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29202173 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KMT2AGLAHPGDGAA | |
| SCHEMBL2163853 | 0.80 | SIGMAR1 (0.49) | ALDH1A1HPGDHSD17B10TDP1TSHR | |
| SCHEMBL30100561 | 0.80 | SIGMAR1 (0.49) | ALDH1A1HPGDHSD17B10TDP1TSHR | |
| SCHEMBL93696 | 0.79 | ALDH1A1 (0.51) | ALDH1A1KMT2AGLAHPGDGAA | |
| SCHEMBL2872359 | 0.79 | KDM4E (0.55) | ALDH1A1KMT2AGLAHPGDGAA | |
| Hydrochloric Acid SCHEMBL28229055 | 0.78 | SIGMAR1 (0.47) | ALDH1A1HPGDHSD17B10TDP1TSHR | |
| Bromide SCHEMBL8003449 | 0.77 | KDM4E (0.53) | ALDH1A1KMT2AGLAHPGDGAA | |
| Hydrochloric Acid SCHEMBL8003436 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KMT2AGLAHPGDGAA | |
| SCHEMBL6652646 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KMT2AGLAHPGDGAA | |
| SCHEMBL9755385 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KMT2AGLAHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019722-B1 | POLYMERIC FLUOROPHORES ENHANCED BY MOIETIES PROVIDING A HYDROPHOBIC AND CONFORMATIONALLY RESTRICTIVE MICROENVIRONMENT | ABBOTT LAB (US) | 2003-04-09 | — | — | EP | claimed |
| EP-1019722-A1 | POLYMERIC FLUOROPHORES ENHANCED BY MOIETIES PROVIDING A HYDROPHOBIC AND CONFORMATIONALLY RESTRICTIVE MICROENVIRONMENT | Abbott Laboratories (US) | 2000-07-19 | — | — | EP | claimed |
| WO-1997028447-A1 | POLYMERIC FLUOROPHORES ENHANCED BY MOIETIES PROVIDING A HYDROPHOBIC AND CONFORMATIONALLY RESTRICTIVE MICROENVIRONMENT | ABBOTT LABORATORIES (US) | 1997-08-07 | — | — | WO | claimed |
| EP-1019722-A1 | POLYMERIC FLUOROPHORES ENHANCED BY MOIETIES PROVIDING A HYDROPHOBIC AND CONFORMATIONALLY RESTRICTIVE MICROENVIRONMENT | Abbott Laboratories (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1997028447-A1 | POLYMERIC FLUOROPHORES ENHANCED BY MOIETIES PROVIDING A HYDROPHOBIC AND CONFORMATIONALLY RESTRICTIVE MICROENVIRONMENT | ABBOTT LABORATORIES (US) | 1997-08-07 | — | — | WO | disclosed |