SCHEMBL704407

SCHEMBL704407

CC(=O)C(O)COP(=O)(O)O

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.65
PGK2 P07205 1/20 0.65
PGD P52209 5/20 0.50
MPI P34949 1/20 0.45
LPAR5 Q9H1C0 2/20 0.41
LPAR6 P43657 1/20 0.41
LPAR1 Q92633 1/20 0.41
LPAR4 Q99677 1/20 0.41
LPAR2 Q9HBW0 1/20 0.41
LPAR3 Q9UBY5 1/20 0.41
ENPP2 Q13822 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31022168 1.00 PGK1 (0.65) PGK1PGK2PGDMPILPAR5
SCHEMBL5792596 0.84 PGK1 (0.52) PGK1PGK2PGDMPILPAR5
SCHEMBL16449212 0.83 PGK1 (0.61) PGK1PGK2PGDMPILPAR5
SCHEMBL30606836 0.83 PGK1 (0.61) PGK1PGK2PGDMPILPAR5
SCHEMBL11860852 0.79 PGK1 (0.57) PGK1PGK2PGDMPILPAR5
3-Phosphoglyceric Acid SCHEMBL2497743 0.79 PGK1 (1.00) PGK1PGK2PGDMPILPAR5
3-Phosphoglyceric Acid SCHEMBL30428419 0.79 PGK1 (1.00) PGK1PGK2PGDMPILPAR5
3-Phosphoglyceric Acid SCHEMBL27483 0.79 PGK1 (1.00) PGK1PGK2PGDMPILPAR5
3-Phosphoglyceric Acid SCHEMBL27482 0.79 PGK1 (1.00) PGK1PGK2PGDMPILPAR5
SCHEMBL158903 0.78 PGD (0.68) PGK1PGK2PGDMPILPAR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 336 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240011067-A1 LIMOSILACTOBACILLUS REUTERI STRAIN WITH HIGH RIBOFLAVIN PRODUCTION AND USES THEREOF UNIVERSITEIT ANTWERPEN (BE) 2024-01-11 US claimed
EP-4251733-A1 <SMALLCAPS/>? ? ?LIMOSILACTOBACILLUS REUTERI? ? ? ? ?STRAIN WITH HIGH RIBOFLAVIN PRODUCTION AND USES THEREOF Universiteit Antwerpen (BE) 2023-10-04 EP claimed
WO-2022112609-A1 LIMOSILACTOBACILLUS REUTERI STRAIN WITH HIGH RIBOFLAVIN PRODUCTION AND USES THEREOF UNIVERSITEIT ANTWERPEN (BE) 2022-06-02 WO claimed
US-9637766-B2 Host cells and methods for producing 1-deoxyxylulose 5-phosphate (DXP) and/or a DXP derived compound THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-05-02 US claimed
US-20160298153-A1 Host Cells and Methods for Producing 1-Deoxyxylulose 5-phosphate (DXP) and/or a DXP Derived Compound THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-10-13 US claimed
US-9382553-B2 Host cells and methods for producing 1-deoxyxylulose 5-phosphate (DXP) and/or a DXP derived compound THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-07-05 US claimed
US-8790900-B2 Microorganisms having enhanced sucrose mutase activity Südzucker Aktiengesellschaft Mannheim/Ochsenfurt (DE) 2014-07-29 US claimed
US-8494779-B2 Method for screening essential metabolites in growth of microorganisms KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2013-07-23 US claimed
WO-2011034263-A1 METHOD FOR PREDICTING A DRUG TARGET IN PATHOGENIC MICROORGANISMS USING AN ESSENTIAL METABOLITE 한국과학기술원 (KR) 2011-03-24 WO claimed
WO-2011034397-A2 METHOD FOR PREDICTING DRUG TARGETS AND SCREENING FOR DRUGS FOR PATHOGENIC MICROORGANISMS USING ESSENTIAL METABOLITES 한국과학기술원 (KR) 2011-03-24 WO claimed
WO-2008078911-A1 METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-07-03 WO claimed
EP-0821063-B1 Improved riboflavin production HOFFMANN LA ROCHE (CH) 2003-12-10 EP claimed
WO-2001018233-A9 SCREENING FOR INHIBITORS OF LUMAZINE SYNTHASE BACHER ADELBERT (DE) 2002-09-06 WO claimed
EP-1208221-A2 SCREENING FOR INHIBITORS OF LUMAZINE SYNTHASE Bacher, Adelbert (DE) 2002-05-29 EP claimed
US-6322995-B1 RECOMBINANT GRAM POSITIVE BACTERIUM USED FOR PRODUCING RIBOFLAVIN F. HOFFMANN-LA ROCHE AG (CH) 2001-11-27 US claimed
EP-1141381-A1 METHOD FOR SCREENING FOR INHIBITORS OF RIBOFLAVIN BIOSYNTHESIS Bacher, Adelbert (DE) 2001-10-10 EP claimed
WO-2001018233-A2 SCREENING FOR INHIBITORS OF LUMAZINE SYNTHASE BACHER ADELBERT (DE) 2001-03-15 WO claimed
EP-1051504-A2 RIBOFLAVIN BIOSYNTHESIS GENES FROM PLANTS AND USES THEREOF Novartis AG (CH) 2000-11-15 EP claimed
WO-2000040744-A1 METHOD FOR SCREENING FOR INHIBITORS OF RIBOFLAVIN BIOSYNTHESIS BACHER ADELBERT (DE) 2000-07-13 WO claimed
WO-1999038986-A2 RIBOFLAVIN BIOSYNTHESIS GENES FROM PLANTS AND USES THEREOF NOVARTIS AG (CH) 1999-08-05 WO claimed