Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10433483 | 0.81 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1TDP1CASP7 | |
| SCHEMBL513737 | 0.81 | MAPK1 (0.56) | ALDH1A1MAPK1L3MBTL1TDP1CASP7 | |
| SCHEMBL12655445 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1TDP1CASP7 | |
| SCHEMBL728448 | 0.76 | MEN1 (0.61) | ALDH1A1MAPK1L3MBTL1TDP1CASP7 | |
| SCHEMBL397773 | 0.76 | MAPK1 (0.77) | ALDH1A1MAPK1L3MBTL1TDP1CASP7 | |
| SCHEMBL28888390 | 0.76 | ALDH1A1 (0.70) | ALDH1A1MAPK1L3MBTL1TDP1CASP7 | |
| SCHEMBL9062960 | 0.75 | MEN1 (0.59) | ALDH1A1MAPK1L3MBTL1TDP1CASP7 | |
| SCHEMBL1993508 | 0.75 | MEN1 (0.59) | ALDH1A1MAPK1L3MBTL1TDP1CASP7 | |
| Ammonia Solution, Strong SCHEMBL2832169 | 0.75 | MEN1 (0.59) | ALDH1A1MAPK1L3MBTL1TDP1CASP7 | |
| Ammonia Solution, Strong SCHEMBL9616083 | 0.75 | MEN1 (0.59) | ALDH1A1MAPK1L3MBTL1TDP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149094-B1 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2004-04-21 | — | — | EP | disclosed |
| US-6376491-B1 | BENZOFURAN DERIVATIVES FOR TREATMENT OR PREVENTION OF MYCOSIS IN MAMMALS | BASILEA PHARMACEUTICA AG (CH) | 2002-04-23 | — | — | US | disclosed |
| EP-1149094-A2 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | Basilea Pharmaceutica AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000037464-A2 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2000-06-29 | — | — | WO | disclosed |