Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 10/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 8/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6017806 | 0.96 | ENPP3 (0.32) | ENPP3ENPP1ENPP2ACE2 | |
| SCHEMBL6017766 | 0.94 | ENPP3 (0.31) | ENPP3ENPP1ENPP2 | |
| SCHEMBL6017898 | 0.93 | KCNH3 (0.32) | ENPP3ENPP1ENPP2 | |
| SCHEMBL6018120 | 0.89 | ENPP3 (0.30) | ENPP3ENPP1ENPP2 | |
| SCHEMBL5036606 | 0.89 | ENPP3 (0.33) | ENPP3ENPP1ENPP2CA12CA1 | |
| SCHEMBL6017660 | 0.88 | ENPP3 (0.33) | ENPP3ENPP1ENPP2ALDH1A1KDM4E | |
| SCHEMBL6018066 | 0.87 | ENPP3 (0.31) | ENPP3ENPP1ENPP2ALDH1A1KDM4E | |
| SCHEMBL6017897 | 0.86 | ENPP3 (0.33) | ENPP3ENPP1ENPP2ALDH1A1KDM4E | |
| SCHEMBL5037949 | 0.86 | CNR2 (0.33) | ENPP3ENPP1ENPP2CA12CA1 | |
| SCHEMBL5141386 | 0.86 | HTR6 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432417-A2 | SUBSTITUTED BENZIMIDAZOLE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCER | Aventis Pharma S.A. (FR) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003028721-A2 | SUBSTITUTED BENZIMIDAZOLE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCER | AVENTIS PHARMA S.A. (FR) | 2003-04-10 | — | — | WO | disclosed |