Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL64069 | 0.86 | AKR1C3 (0.57) | MAPTLMNAPKMMEN1KMT2A | |
| SCHEMBL1331831 | 0.86 | AKR1C3 (0.57) | MAPTLMNAPKMMEN1KMT2A | |
| SCHEMBL9798109 | 0.84 | LIG1 (0.59) | LIG1MAPTLMNAHPGDESR1 | |
| SCHEMBL7673359 | 0.84 | AKR1C3 (0.61) | MAPTLMNAHPGDMEN1KMT2A | |
| SCHEMBL9130311 | 0.84 | NR4A1 (0.61) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL9614636 | 0.82 | LIG1 (0.79) | LIG1MAPTLMNAHPGDESR1 | |
| SCHEMBL14995290 | 0.81 | MAPT (0.50) | LIG1MAPTLMNAHPGDESR1 | |
| SCHEMBL9080792 | 0.80 | KMT2A (0.62) | MAPTLMNAHPGDHTTMEN1 | |
| SCHEMBL4358130 | 0.80 | MAPT (0.56) | LIG1MAPTLMNAHPGDESR1 | |
| SCHEMBL10640903 | 0.79 | MEN1 (0.59) | LIG1MAPTLMNAHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040260071-A1 | Benzophene-linked crf and crf-like peptides for covalent labeling of corticotropin-releasing factor crf binding protein | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2004-12-23 | — | — | US | disclosed |
| EP-1402271-A2 | BENZOPHENONE-LINKED CRF AND CRF-LIKE PEPTIDES FOR COVALENT LABELING OF CORTICOTROPIN-RELEASING FACTOR (CRF) BINDING PROTEIN | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002095395-A2 | BENZOPHENONE-LINKED CRF AND CRF-LIKE PEPTIDES FOR COVALENT LABELING OF CORTICOTROPIN-RELEASING FACTOR (CRF) BINDING PROTEIN | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2002-11-28 | — | — | WO | disclosed |