Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1200740 | 0.87 | AKR1C3 (0.55) | LMNAMAPTPKMCES2GAA | |
| SCHEMBL9797365 | 0.84 | LIG1 (0.41) | LIG1LMNAMAPTPKMGAA | |
| SCHEMBL9589641 | 0.84 | AKR1C3 (0.59) | LMNAMAPTHPGDMEN1KMT2A | |
| SCHEMBL7044239 | 0.84 | LIG1 (0.61) | LIG1ESR2LMNAMAPTESR1 | |
| SCHEMBL10420431 | 0.83 | LIG1 (0.49) | LIG1ESR2LMNAMAPTESR1 | |
| SCHEMBL2913776 | 0.82 | ALDH1A1 (0.45) | ESR2LMNAMAPTGAANPSR1 | |
| SCHEMBL9856394 | 0.82 | AKR1C3 (0.41) | LIG1LMNAMAPTPKMMEN1 | |
| SCHEMBL9614636 | 0.80 | LIG1 (0.79) | LIG1ESR2LMNAMAPTESR1 | |
| SCHEMBL27846222 | 0.80 | KMT2A (0.60) | LMNAMAPTHPGDHTTMEN1 | |
| SCHEMBL29007028 | 0.79 | MEN1 (0.57) | LIG1LMNAMAPTHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996347-A | Anticoagulant | FOURNIER INNOVATION ET SYNERGIE (FR) | 1991-02-26 | — | — | US | disclosed |
| US-4877808-A | ANTITHROMBOTICS | FOURNIER INNOVATION ET SYNERGIE (FR) | 1989-10-31 | — | — | US | disclosed |