SCHEMBL7044279

SCHEMBL7044279

Cc1cn([C@H]2CC[C@@H](COP(O)(=S)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.58
POLA1 P09884 1/20 0.58
POLD1 P28340 1/20 0.58
TK1 P04183 7/20 0.52
BCHE P06276 1/20 0.47
ALB P02768 1/20 0.44
PKM P14618 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triphosphate SCHEMBL27892350 0.92 POLB (0.61) POLBPOLA1POLD1TK1BCHE
SCHEMBL18855348 0.91 POLB (0.68) POLBPOLA1POLD1TK1BCHE
SCHEMBL77582 0.91 POLB (0.68) POLBPOLA1POLD1TK1BCHE
SCHEMBL3031874 0.91 POLB (0.68) POLBPOLA1POLD1TK1BCHE
SCHEMBL265387 0.91 POLB (0.68) POLBPOLA1POLD1TK1BCHE
SCHEMBL30586988 0.91 POLB (0.68) POLBPOLA1POLD1TK1BCHE
SCHEMBL154177 0.91 POLB (0.65) POLBPOLA1POLD1TK1BCHE
SCHEMBL28961478 0.87 POLB (0.61) POLBPOLA1POLD1TK1ALB
Triphosphate SCHEMBL6138574 0.87 POLB (0.58) POLBPOLA1POLD1TK1BCHE
SCHEMBL23440065 0.87 TK1 (0.67) POLBPOLA1POLD1TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4521509-A Method for degrading DNA RESEARCH CORPORATION (US) 1985-06-04 US claimed
US-20240084367-A1 CELL BARCODING COMPOSITIONS AND METHODS FACTORIAL DIAGNOSTICS, INC. (US) 2024-03-14 US disclosed
EP-4271389-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA Rejuvenation Technologies Inc. (US) 2023-11-08 EP disclosed
WO-2022147039-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES INC. (US) 2022-07-07 WO disclosed
US-11142788-B2 Isolation of target nucleic acids GENETICS RESEARCH, LLC (US) 2021-10-12 US disclosed
US-20180355406-A1 POLYNUCLEIC ACID MOLECULE ENRICHMENT METHODOLOGIES GENETICS RESEARCH, LLC, D/B/A ZS GENETICS, INC. 2018-12-13 US disclosed
US-20180355419-A1 ISOLATION OF TARGET NUCLEIC ACIDS HARBINGER HEALTH, INC. 2018-12-13 US disclosed
US-20030157499-A1 Method of assessing the amount of nucleic acid in a sample BIOTAGE AB (SE) 2003-08-21 US disclosed
WO-2001042496-A2 A METHOD OF ASSESSING THE AMOUNT OF NUCLEIC ACID IN A SAMPLE PYROSEQUENCING AB (SE) 2001-06-14 WO disclosed