Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.44 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.36 |
| ▸ | STAT3 | P40763 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049003 | 0.81 | SMN1; SMN2 (0.62) | CASP3CHUKTXNRD1NOX4MAPT | |
| SCHEMBL7051693 | 0.80 | CHUK (0.68) | CASP3CHUKTXNRD1NOX4MAPT | |
| SCHEMBL6449108 | 0.80 | MAPT (0.39) | CASP3MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6453925 | 0.80 | CHUK (0.46) | CASP3CHUKTXNRD1NOX4MAPT | |
| SCHEMBL6451167 | 0.79 | TP53 (0.63) | MAPTKDM4EALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL7048686 | 0.77 | CASP3 (0.52) | CASP3CHUKTXNRD1NOX4NPC1 | |
| SCHEMBL7153588 | 0.75 | CASP3 (0.53) | CASP3CHUKTXNRD1NOX4KDM4E | |
| SCHEMBL6450097 | 0.73 | SMN1; SMN2 (0.59) | CASP3CHUKTXNRD1NOX4MAPT | |
| SCHEMBL6449975 | 0.72 | S1PR1 (0.50) | CASP3CHUKTXNRD1NOX4MAPT | |
| SCHEMBL6448883 | 0.71 | CASP3 (0.48) | CASP3CHUKTXNRD1NOX4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004110351-A2 | HETEROCYCLIC COMPOUNDS FOR TREATING HEPATITIS C VIRUS | ANADYS PHARMACEUTICALS, INC. (US) | 2004-12-23 | — | — | WO | disclosed |