Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | CASP3 | P42574 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CHUK | O15111 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051693 | 0.84 | CHUK (0.68) | SMN1; SMN2HPGDMAPTKDM4EALDH1A1 | |
| SCHEMBL13247920 | 0.82 | MAPT (0.47) | HPGDMAPTKDM4EALDH1A1NPC1 | |
| SCHEMBL7044304 | 0.81 | CASP3 (0.50) | SMN1; SMN2HPGDMAPTKDM4EALDH1A1 | |
| SCHEMBL4193214 | 0.77 | SMN1; SMN2 (1.00) | SMN1; SMN2HPGDMAPTKDM4EALDH1A1 | |
| SCHEMBL6459405 | 0.77 | NPC1 (0.40) | SMN1; SMN2HPGDMAPTKDM4EALDH1A1 | |
| SCHEMBL6457424 | 0.75 | CASP3 (0.48) | SMN1; SMN2HPGDMAPTKDM4EALDH1A1 | |
| SCHEMBL28133798 | 0.74 | SMN1; SMN2 (0.77) | SMN1; SMN2HPGDMAPTKDM4EALDH1A1 | |
| SCHEMBL7153588 | 0.74 | CASP3 (0.53) | KDM4ENPC1CASP3LMNACHUK | |
| SCHEMBL7048686 | 0.73 | CASP3 (0.52) | NPC1CASP3RAB9ACHUKTXNRD1 | |
| SCHEMBL22925608 | 0.73 | CASP3 (0.56) | KDM4ECASP3LMNANPSR1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004110351-A2 | HETEROCYCLIC COMPOUNDS FOR TREATING HEPATITIS C VIRUS | ANADYS PHARMACEUTICALS, INC. (US) | 2004-12-23 | — | — | WO | disclosed |