Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 3/20 | 0.68 |
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.68 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.68 |
| ▸ | CASP3 | P42574 | 7/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 5/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 5/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7153588 | 0.85 | CASP3 (0.53) | CHUKTXNRD1NOX4CASP3SENP8 | |
| SCHEMBL7048686 | 0.84 | CASP3 (0.52) | CHUKTXNRD1NOX4CASP3SENP8 | |
| SCHEMBL7049003 | 0.84 | SMN1; SMN2 (0.62) | CHUKTXNRD1NOX4CASP3KDM4E | |
| SCHEMBL7158427 | 0.81 | CASP3 (0.49) | CHUKTXNRD1NOX4CASP3KDM4E | |
| SCHEMBL16915425 | 0.80 | HSD17B10 (0.48) | CHUKTXNRD1NOX4KDM4EALDH1A1 | |
| SCHEMBL6448883 | 0.80 | CASP3 (0.48) | CHUKTXNRD1NOX4CASP3MAPT | |
| SCHEMBL7044304 | 0.80 | CASP3 (0.50) | CHUKTXNRD1NOX4CASP3KDM4E | |
| SCHEMBL6457424 | 0.79 | CASP3 (0.48) | CHUKTXNRD1NOX4CASP3KDM4E | |
| SCHEMBL4198081 | 0.76 | SMN1; SMN2 (0.68) | CHUKTXNRD1NOX4CASP3SENP8 | |
| SCHEMBL6450106 | 0.76 | ADORA2A (0.53) | CHUKTXNRD1NOX4CASP3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004110351-A2 | HETEROCYCLIC COMPOUNDS FOR TREATING HEPATITIS C VIRUS | ANADYS PHARMACEUTICALS, INC. (US) | 2004-12-23 | — | — | WO | disclosed |