Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7044566 | 1.00 | BCHE (0.46) | BCHEACHEMCHR1SMN1; SMN2LMNA | |
| SCHEMBL6868667 | 0.92 | ALPL (0.52) | MCHR1SMN1; SMN2LMNAPKMADRA2A | |
| SCHEMBL6868673 | 0.92 | ALPL (0.52) | MCHR1SMN1; SMN2LMNAPKMADRA2A | |
| SCHEMBL6868980 | 0.91 | LMNA (0.55) | MCHR1LMNAPKMADRA2AALPL | |
| SCHEMBL6875979 | 0.91 | LMNA (0.54) | MCHR1SMN1; SMN2LMNAPKMADRA2A | |
| SCHEMBL6875974 | 0.91 | LMNA (0.54) | MCHR1SMN1; SMN2LMNAPKMADRA2A | |
| SCHEMBL6868978 | 0.91 | LMNA (0.55) | MCHR1LMNAPKMADRA2AALPL | |
| SCHEMBL6868868 | 0.91 | KMT2A (0.56) | ACHEMCHR1SMN1; SMN2LMNAADRA2A | |
| SCHEMBL6868863 | 0.91 | KMT2A (0.56) | ACHEMCHR1SMN1; SMN2LMNAADRA2A | |
| SCHEMBL6879414 | 0.90 | MCHR1 (0.46) | MCHR1SMN1; SMN2LMNAPKMADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |