Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CCKAR | P32238 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7041089 | 0.90 | THRB (0.38) | KMT2AL3MBTL1NPC1RAB9AKDM4E | |
| SCHEMBL7042006 | 0.89 | RBP4 (0.44) | SMN1; SMN2KMT2AL3MBTL1RAB9AGAA | |
| SCHEMBL7042753 | 0.89 | MAPT (0.47) | SMN1; SMN2KMT2ANPC1RAB9AGAA | |
| SCHEMBL7041121 | 0.86 | MAPT (0.48) | SMN1; SMN2KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL6657909 | 0.86 | ALDH1A1 (0.50) | SMN1; SMN2KMT2AL3MBTL1GAAKDM4E | |
| SCHEMBL7038717 | 0.82 | KMT2A (0.41) | SMN1; SMN2KMT2AL3MBTL1GAACCKAR | |
| SCHEMBL7040077 | 0.82 | MAPT (0.41) | SMN1; SMN2KMT2AL3MBTL1NPC1GAA | |
| SCHEMBL7041068 | 0.82 | KMT2A (0.39) | SMN1; SMN2KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL7044475 | 0.81 | GAA (0.41) | SMN1; SMN2KMT2AL3MBTL1GAACCKAR | |
| SCHEMBL7046056 | 0.80 | GAA (0.39) | SMN1; SMN2KMT2AL3MBTL1GAACCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030092910-A1 | Piperazine derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2003-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092910-A1 | Piperazine derivatives and process for the preparation thereof | CBR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HCCS | SMN1; SMN2 2466/4885KMT2A 2664/4885L3MBTL1 2717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.