Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7043251 | 0.89 | TACR1 (0.39) | CA1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL11258611 | 0.83 | SLC6A3 (0.39) | SLC6A2SLC6A4SLC6A3ALDH1A1L3MBTL1 | |
| SCHEMBL14177731 | 0.76 | ALDH1A1 (0.46) | SLC6A2SLC6A4SLC6A3ALDH1A1MCOLN3 | |
| SCHEMBL6734281 | 0.74 | L3MBTL1 (0.43) | ALDH1A1L3MBTL1CTSD | |
| SCHEMBL12210573 | 0.74 | L3MBTL1 (0.43) | ALDH1A1L3MBTL1CTSD | |
| SCHEMBL10160076 | 0.74 | L3MBTL1 (0.43) | ALDH1A1L3MBTL1CTSD | |
| SCHEMBL11475684 | 0.73 | CA1 (0.64) | CA1POLBALDH1A1TACR1L3MBTL1 | |
| SCHEMBL6413564 | 0.72 | TACR1 (0.40) | CA1SLC6A2SLC6A4SLC6A3TACR1 | |
| Hydrochloric Acid SCHEMBL6413723 | 0.71 | TACR1 (0.41) | CA1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL2312034 | 0.69 | DDB1 (0.53) | POLBALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007940-A1 | LACTAM AND THIOLACTAM DERIVATIVES AS ANESTHETIC AND CONSCIOUS SEDATION AGENTS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2003-01-30 | — | — | WO | disclosed |