Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046916 | 0.85 | HDAC1 (0.45) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL7044837 | 0.73 | EPHX2 (0.38) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL7046297 | 0.70 | FOLH1 (0.39) | FAAH | |
| SCHEMBL7421214 | 0.69 | FOLH1 (0.48) | — | |
| SCHEMBL7047769 | 0.68 | HDAC1 (0.40) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL7045332 | 0.67 | FOLH1 (0.40) | HDAC6HDAC1HDAC2 | |
| SCHEMBL7049032 | 0.66 | FOLH1 (0.40) | — | |
| SCHEMBL6211869 | 0.65 | FAAH (0.66) | MGLLFAAH | |
| SCHEMBL27823605 | 0.65 | FAAH (0.53) | MGLLFAAH | |
| SCHEMBL27802853 | 0.64 | FAAH (0.67) | MGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | US | disclosed |
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | SERPINB1, CTRL, CTSZ | HDAC6 217/4885HDAC1 304/4885HDAC3 266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.