Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.54 |
| ▸ | PPARA | Q07869 | 12/20 | 0.54 |
| ▸ | PPARD | Q03181 | 11/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 2/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7039665 | 0.85 | PPARD (0.73) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL7039142 | 0.85 | PPARA (0.75) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL8669133 | 0.84 | PPARG (0.53) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL7040931 | 0.83 | PPARA (0.53) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL7042415 | 0.82 | PPARD (0.62) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL7044850 | 0.82 | PPARA (0.69) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL7046234 | 0.81 | PPARD (0.62) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL6559207 | 0.80 | PPARG (0.58) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL7046443 | 0.79 | PPARD (0.60) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL6936685 | 0.79 | PPARG (0.64) | PPARGPPARAPPARDNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882029-B1 | HETEROCYCLIC DERIVATIVES AS ANTIDIABETIC AND ANTIOBESITY AGENTS | MERCK & CO INC (US) | 2003-04-02 | — | — | EP | claimed |