Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGAV | P06756 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 3/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112584 | 0.91 | PLG (0.41) | PLGPLAUF10KLKB1TMPRSS11D | |
| SCHEMBL7043617 | 0.91 | PLG (0.47) | PLGPLAUF10KLKB1TMPRSS11D | |
| SCHEMBL7038739 | 0.89 | PLG (0.43) | PLGPLAUF10KLKB1TMPRSS11D | |
| SCHEMBL8112581 | 0.86 | PLG (0.40) | PLGPLAUF10KLKB1TMPRSS11D | |
| SCHEMBL8118877 | 0.84 | NPY1R (0.41) | PLGPLAUF10KLKB1ITGB3 | |
| SCHEMBL4438826 | 0.81 | SIRT2 (0.44) | PLGPLAUF10KLKB1ITGB3 | |
| SCHEMBL8127032 | 0.80 | ITGB3 (0.36) | PLGPLAUF10KLKB1ITGB3 | |
| SCHEMBL7038734 | 0.80 | PLG (0.47) | PLGPLAUF10KLKB1ITGB3 | |
| SCHEMBL8118879 | 0.80 | PLG (0.38) | PLGPLAUF10KLKB1TMPRSS11D | |
| SCHEMBL8526287 | 0.79 | PLG (0.48) | PLGPLAUF10KLKB1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | disclosed |