Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 3/20 | 0.47 |
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 8/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | AVPR1B | P47901 | 5/20 | 0.35 |
| ▸ | TMPRSS6 | Q8IU80 | 6/20 | 0.35 |
| ▸ | BMP1 | P13497 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526287 | 0.90 | PLG (0.48) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL7038739 | 0.90 | PLG (0.43) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL7043617 | 0.89 | PLG (0.47) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL8529439 | 0.82 | PLG (0.49) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL1740223 | 0.82 | PLG (0.49) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL7020069 | 0.81 | PLG (0.49) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL7045236 | 0.80 | PLG (0.41) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL8526793 | 0.80 | PLG (0.47) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL8526353 | 0.78 | PLG (0.43) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL8526347 | 0.78 | PLG (0.40) | PLGPLAUF10KLKB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | disclosed |