Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8665049 | 0.74 | ALDH1A1 (0.37) | ALDH1A1KDM4EGAAACHEBCHE | |
| SCHEMBL15210855 | 0.73 | ALDH1A1 (0.39) | ALDH1A1KDM4EGAAACHEMEN1 | |
| Hydrochloric Acid SCHEMBL1246276 | 0.72 | ALDH1A1 (0.38) | ALDH1A1KDM4EGAAACHEMEN1 | |
| SCHEMBL17849080 | 0.68 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAAHDAC8ACHE | |
| SCHEMBL30149559 | 0.68 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAAHDAC8ACHE | |
| SCHEMBL17849090 | 0.68 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAAHDAC8ACHE | |
| SCHEMBL31364317 | 0.68 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAAHDAC8ACHE | |
| SCHEMBL1873234 | 0.68 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAAHDAC8ACHE | |
| SCHEMBL29388401 | 0.65 | ALDH1A1 (0.45) | ALDH1A1KDM4EGAAHDAC8ACHE | |
| SCHEMBL2407961 | 0.65 | ALDH1A1 (0.45) | ALDH1A1KDM4EGAAHDAC8ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030064954-A1 | Cationic amphiphilic 1,4-dihydropyridine derivatives useful for delivery of nucleotide containing compounds | SPONDULI SERVICES, LTD. (AU) | 2003-04-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030064954-A1 | Cationic amphiphilic 1,4-dihydropyridine derivatives useful for delivery of nucleotide containing compounds | ACIN1, DNA2, KPNA1 | BCL2 2608/4885ALDH1A1 2344/4885KDM4E 2990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.