Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049357 | 0.93 | MEN1 (0.55) | CNR2POLBTDP1CNR1MEN1 | |
| SCHEMBL7046762 | 0.93 | MEN1 (0.55) | CNR2POLBTDP1CNR1MEN1 | |
| SCHEMBL7045782 | 0.76 | CNR2 (0.53) | CNR2POLBTDP1CNR1MEN1 | |
| SCHEMBL24483324 | 0.74 | PTGER4 (0.54) | POLBKDM4EL3MBTL1SMN1; SMN2HTT | |
| SCHEMBL31383501 | 0.74 | KDM4E (0.60) | CNR2CNR1KDM4EMAPK1NPSR1 | |
| SCHEMBL7049352 | 0.73 | MEN1 (0.49) | CNR2POLBTDP1CNR1MEN1 | |
| SCHEMBL7046760 | 0.73 | MEN1 (0.49) | CNR2POLBTDP1CNR1MEN1 | |
| SCHEMBL25433493 | 0.69 | TSHR (0.51) | CNR2POLBCNR1MEN1KMT2A | |
| SCHEMBL25437053 | 0.68 | NPC1 (0.56) | CNR2CNR1KDM4EALDH1A1 | |
| SCHEMBL27967763 | 0.68 | PGR (0.52) | CNR2CNR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1460064-A1 | Indole-2-carboxamide derivatives useful as beta-2 agonists | Pfizer Limited (GB) | 2004-09-22 | — | — | EP | claimed |