Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.53 |
| ▸ | CNR1 | P21554 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049352 | 0.93 | MEN1 (0.49) | CNR2CNR1POLBTDP1MEN1 | |
| SCHEMBL7046760 | 0.93 | MEN1 (0.49) | CNR2CNR1POLBTDP1MEN1 | |
| SCHEMBL7045786 | 0.76 | CNR2 (0.60) | CNR2CNR1POLBTDP1MEN1 | |
| SCHEMBL7049357 | 0.73 | MEN1 (0.55) | CNR2CNR1POLBTDP1MEN1 | |
| SCHEMBL7046762 | 0.73 | MEN1 (0.55) | CNR2CNR1POLBTDP1MEN1 | |
| SCHEMBL4610877 | 0.67 | KMT2A (0.51) | POLBMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL7046652 | 0.67 | P2RX7 (0.47) | CNR2CNR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7046082 | 0.67 | P2RX7 (0.44) | CNR2CNR1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL27617372 | 0.66 | FOLH1 (0.52) | POLBTDP1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL24483324 | 0.65 | PTGER4 (0.54) | POLBSMN1; SMN2L3MBTL1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1460064-A1 | Indole-2-carboxamide derivatives useful as beta-2 agonists | Pfizer Limited (GB) | 2004-09-22 | — | — | EP | claimed |