Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 4/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046760 | 1.00 | MEN1 (0.49) | MEN1KMT2AL3MBTL1CNR2CNR1 | |
| SCHEMBL7045782 | 0.93 | CNR2 (0.53) | MEN1KMT2AL3MBTL1CNR2CNR1 | |
| SCHEMBL7046762 | 0.74 | MEN1 (0.55) | MEN1KMT2AL3MBTL1CNR2CNR1 | |
| SCHEMBL7049357 | 0.74 | MEN1 (0.55) | MEN1KMT2AL3MBTL1CNR2CNR1 | |
| SCHEMBL4610877 | 0.74 | KMT2A (0.51) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL7046082 | 0.73 | P2RX7 (0.44) | KMT2ACNR2CNR1KDM4ESMN1; SMN2 | |
| SCHEMBL7046652 | 0.73 | P2RX7 (0.47) | MEN1KMT2ACNR2CNR1KDM4E | |
| SCHEMBL7045786 | 0.73 | CNR2 (0.60) | MEN1KMT2AL3MBTL1CNR2CNR1 | |
| SCHEMBL4613206 | 0.72 | MEN1 (0.41) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL6746510 | 0.72 | P2RX7 (0.48) | MEN1KMT2ACNR2CNR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1460064-A1 | Indole-2-carboxamide derivatives useful as beta-2 agonists | Pfizer Limited (GB) | 2004-09-22 | — | — | EP | claimed |
| EP-1460064-A1 | Indole-2-carboxamide derivatives useful as beta-2 agonists | Pfizer Limited (GB) | 2004-09-22 | — | — | EP | disclosed |