SCHEMBL7045865

SCHEMBL7045865

CC(C)(c1cc(Cl)c(OCCO)c(Cl)c1)c1cc(Cl)c(OCCO)c(Cl)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.38
CYP3A4 P08684 3/20 0.38
PLAU P00749 1/20 0.38
ALDH1A1 P00352 6/20 0.36
S1PR1 P21453 2/20 0.35
S1PR3 Q99500 2/20 0.35
HPGD P15428 4/20 0.34
MAPT P10636 3/20 0.34
CYP2C19 P33261 2/20 0.34
MAPK1 P28482 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TDP1 Q9NUW8 3/20 0.33
KDM4E B2RXH2 4/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
AR P10275 1/20 0.32
RECQL P46063 2/20 0.31
HSD17B10 Q99714 2/20 0.31
GAA P10253 2/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3002181 0.91 SMN1; SMN2 (0.37) SMN1; SMN2PLAUALDH1A1S1PR1S1PR3
SCHEMBL19484550 0.89 SMN1; SMN2 (0.51) SMN1; SMN2CYP3A4ALDH1A1HPGDMAPT
SCHEMBL11654743 0.84 SMN1; SMN2 (0.36) SMN1; SMN2CYP3A4PLAUALDH1A1S1PR1
SCHEMBL25899 0.81 ALDH1A1 (0.54) SMN1; SMN2CYP3A4ALDH1A1HPGDTDP1
SCHEMBL347042 0.81 HTR1A (0.43) SMN1; SMN2CYP3A4ALDH1A1S1PR1S1PR3
SCHEMBL8997268 0.80 MCL1 (0.47) SMN1; SMN2CYP3A4PLAUALDH1A1CYP2C19
SCHEMBL660641 0.79 MAPT (0.51) SMN1; SMN2PLAUALDH1A1HPGDMAPT
SCHEMBL11349119 0.79 LMNA (0.41) SMN1; SMN2CYP3A4ALDH1A1HPGDMAPT
SCHEMBL26748925 0.78 KDM4E (0.43) SMN1; SMN2CYP3A4ALDH1A1TDP1KDM4E
SCHEMBL26746294 0.78 KDM4E (0.43) SMN1; SMN2CYP3A4ALDH1A1TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4180470-A WEAR RESISTANCE LEVER BROTHERS COMPANY (US) 1979-12-25 US claimed
EP-0751183-B1 Thermo-shrinkable polyester films TOYO BOSEKI (JP) 2003-04-09 EP disclosed
EP-0271928-B1 Thermo-shrinkable polyester film TOYO BOSEKI (JP) 1997-04-16 EP disclosed
EP-0751183-A2 A polyester composition used for thermoshrinkable films Toyo Boseki Kabushiki Kaisha (JP) 1997-01-02 EP disclosed
US-4996291-A Wrapping material TOYO BOSEKI KABUSHIKI KAISHA (JP) 1991-02-26 US disclosed
US-4921890-A Process for improving polymer substrate properties, and flame retardancy modified polymers produced thereby INTERA COMPANY, LTD. (US) 1990-05-01 US disclosed
EP-0294531-A2 Treatment of polymer substrates Intera Company, Ltd (US) 1988-12-14 EP disclosed
EP-0271928-A2 Thermo-shrinkable polyester film Toyo Boseki Kabushiki Kaisha (JP) 1988-06-22 EP disclosed
US-4525529-A HALOGEN-CONTAINING COPOLYMERIC POLYESTER BLENDED WITH MODIFIED ETHYLENE COPOLYMER MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1985-06-25 US disclosed
US-4454302-A BLEND WITH HALOGEN CONTAINING ACRYLIC RESIN MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1984-06-12 US disclosed
US-4134814-A Halogenated photopolymerizable adhesives UCB, SOCIETE ANONYME (BE) 1979-01-16 US disclosed
US-4134811-A Halogenated photopolymerizable compositions UCB, SOCIETE ANONYME (BE) 1979-01-16 US disclosed
US-4086208-A Flame resistant polyesters TOYO BOSEKI KABUSHIKI KAISHA (JA) 1978-04-25 US disclosed
US-4059546-A Textile fiber blend comprising cellulosic fibers and ethylene 2,6-naphthalene dicarboxylate-halogenated comonomers copolyester fibers AVTEX FIBERS INC. (US) 1977-11-22 US disclosed
US-4053439-A METAL SALT OF AROMATIC CARBOXYLATE ARMSTRONG CORK COMPANY (US) 1977-10-11 US disclosed