SCHEMBL6561561

SCHEMBL6561561

C=CCOc1ccc(C=O)c(O)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.57
TYR P14679 1/20 0.57
TRIM33 Q9UPN9 1/20 0.57
HPGD P15428 3/20 0.57
MAPT P10636 3/20 0.57
ALDH1A1 P00352 2/20 0.57
GAA P10253 2/20 0.57
POLB P06746 1/20 0.50
SLC5A1 P13866 1/20 0.48
SLC5A2 P31639 1/20 0.48
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
CA12 O43570 3/20 0.46
CA1 P00915 3/20 0.46
CA9 Q16790 3/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
ALDH2 P05091 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22278278 0.87 ERN1 (0.57) TRIM24TYRTRIM33HPGDMAPT
SCHEMBL13956284 0.84 HPGD (0.51) TRIM24TYRTRIM33HPGDMAPT
SCHEMBL1520406 0.81 ALDH1A1 (0.47) HPGDMAPTALDH1A1GAALMNA
SCHEMBL8128077 0.81 HPGD (0.65) HPGDMAPTALDH1A1GAASLC5A1
SCHEMBL7180109 0.81 TYR (0.58) TRIM24TYRTRIM33HPGDMAPT
SCHEMBL8128073 0.81 HPGD (0.65) HPGDMAPTALDH1A1GAASLC5A1
SCHEMBL29509997 0.80 MAPT (0.53) HPGDMAPTALDH1A1GAASLC5A1
SCHEMBL6931077 0.80 CA12 (0.44) HPGDMAPTALDH1A1GAALMNA
SCHEMBL7046014 0.80 TDP1 (0.47) HPGDMAPTALDH1A1GAALMNA
SCHEMBL28011522 0.80 CA12 (0.46) HPGDMAPTALDH1A1GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119241976-A Cation modified soft PVC (polyvinyl chloride) membrane material and preparation method thereof 南通吉美装饰材料有限公司 2025-01-03 CN claimed
CN-119241976-A Cation modified soft PVC (polyvinyl chloride) membrane material and preparation method thereof 南通吉美装饰材料有限公司 2025-01-03 CN disclosed
CN-112672873-B Resin composition suitable for printing and printing method 莱奥本矿业大学 2024-02-02 CN disclosed
CN-116284218-A Method for synthesizing palmitoyl tripeptide-1 based on liquid phase carrier assistance 常州大学 2023-06-23 CN disclosed
US-7538123-B2 Indole derivative having piperidine ring EISAI R & D MANAGEMENT CO., LTD. (JP) 2009-05-26 US disclosed
US-7538123-B2 Indole derivative having piperidine ring EISAI R & D MANAGEMENT CO., LTD. (JP) 2009-05-26 US disclosed
US-20070219179-A1 Indole Derivative Having Piperidine Ring EISAI R&D MANAGEMENT CO., LTD. (JP) 2007-09-20 US disclosed
US-20070219179-A1 Indole Derivative Having Piperidine Ring EISAI R&D MANAGEMENT CO., LTD. (JP) 2007-09-20 US disclosed
EP-1757599-A1 INDOLE DERIVATIVES HAVING PIPERIDINE RINGS Eisai R&D Management Co., Ltd. (JP) 2007-02-28 EP disclosed
EP-0904079-B1 ANTIDIABETIC AGENTS MERCK & CO INC (US) 2004-03-24 EP disclosed
US-6124343-A Substituted phenyl compounds with a substituent having a thienyl ring RHONE-POULENC RORER LIMITED (GB) 2000-09-26 US disclosed
EP-0805802-B1 SUBSTITUTED PHENYL COMPOUNDS AS ENDOTHELIN ANTAGONISTS RHONE POULENC RORER LTD (GB) 2000-08-16 EP disclosed
US-6048893-A Substituted phenyl compounds with a substituent having A 1,3-benzodioxole ring RHONE-POULENC RORER LIMITED (GB) 2000-04-11 US disclosed
EP-0904079-A4 1999-05-06 EP disclosed
EP-0904079-A1 ANTIDIABETIC AGENTS Merck & Co., Inc. (US) 1999-03-31 EP disclosed
US-5859051-A ACETYLPHENOL DERIVATIVES MERCK & CO., INC. (US) 1999-01-12 US disclosed
CN-1178525-A Substituted phenyl compounds as endothelin antagonists RHONE POULEUC RORER LTD (GB) 1998-04-08 CN disclosed
EP-0805802-A1 SUBSTITUTED PHENYL COMPOUNDS AS ENDOTHELIN ANTAGONISTS RHONE-POULENC RORER LIMITED (GB) 1997-11-12 EP disclosed
WO-1997027857-A1 ANTIDIABETIC AGENTS MERCK & CO., INC. (US) 1997-08-07 WO disclosed
WO-1996022978-A1 SUBSTITUTED PHENYL COMPOUNDS AS ENDOTHELIN ANTAGONISTS RHONE POULENC RORER LIMITED (GB) 1996-08-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070219179-A1 Indole Derivative Having Piperidine Ring HTR5A, HTR2C, HTR1A TRIM24 2822/4885TYR 1204/4885TRIM33 2898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.