SCHEMBL7046038

SCHEMBL7046038

CCOC(=O)C(CC)(CC1CCCCC1)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.38
GRM2 Q14416 1/20 0.37
GRM3 Q14832 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 4/20 0.36
MAPT P10636 1/20 0.35
LMNA P02545 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
THRB P10828 1/20 0.35
ATM Q13315 1/20 0.35
TSHR P16473 1/20 0.34
CNR2 P34972 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
FFAR1 O14842 1/20 0.33
FKBP1A P62942 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5413788 0.84 KDM4E (0.38) METAP2MEN1KMT2AALDH1A1MAPT
SCHEMBL11005384 0.80 CYP1A2 (0.42) METAP2MEN1KMT2AALDH1A1MAPT
SCHEMBL8329421 0.80 METAP2 (0.40) METAP2MEN1KMT2AALDH1A1MAPT
SCHEMBL11465149 0.78 CYP1A2 (0.43) METAP2MEN1KMT2AALDH1A1LMNA
SCHEMBL8331541 0.78 SIGMAR1 (0.38) METAP2MEN1KMT2AALDH1A1LMNA
SCHEMBL456197 0.77 MEN1 (0.48) MEN1KMT2AALDH1A1LMNAL3MBTL1
SCHEMBL10711183 0.77 SMN1; SMN2 (0.48) CYP1A2SMN1; SMN2FKBP1A
SCHEMBL7781964 0.77 MEN1 (0.47) METAP2MEN1KMT2AALDH1A1MAPT
SCHEMBL7785264 0.77 MEN1 (0.47) METAP2MEN1KMT2AALDH1A1MAPT
SCHEMBL5728518 0.77 ALDH1A1 (0.35) METAP2GRM2GRM3ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0912617-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SPA (IT) 2003-04-16 EP claimed
US-6313238-B1 POLYMERIZATION OF ALPHA-OLEFINS IN PRESENCE OF POLYMERIZATION CATALYST SYSTEM COMPRISING REACTION PRODUCT OF TITANIUM COMPOUND, AND ELECTRON DONOR COMPRISING MALONIC ESTER SUPPORTED ON MAGNESIUM HALIDE, ALKYLALUMINUM COMPOUND BASELL TECHNOLOGY COMPANY BV (NL) 2001-11-06 US claimed
US-6048818-A Components and catalysts for the polymerization of olefins MONTELL TECHNOLOGY COMPANY BV (NL) 2000-04-11 US claimed
EP-0912617-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SPA (IT) 2003-04-16 EP disclosed
US-6313238-B1 POLYMERIZATION OF ALPHA-OLEFINS IN PRESENCE OF POLYMERIZATION CATALYST SYSTEM COMPRISING REACTION PRODUCT OF TITANIUM COMPOUND, AND ELECTRON DONOR COMPRISING MALONIC ESTER SUPPORTED ON MAGNESIUM HALIDE, ALKYLALUMINUM COMPOUND BASELL TECHNOLOGY COMPANY BV (NL) 2001-11-06 US disclosed
US-6048818-A Components and catalysts for the polymerization of olefins MONTELL TECHNOLOGY COMPANY BV (NL) 2000-04-11 US disclosed
EP-0912617-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Montell Technology Company bv (NL) 1999-05-06 EP disclosed
WO-1998056833-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS MONTELL TECHNOLOGY COMPANY B.V. (NL) 1998-12-17 WO disclosed