Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13933322 | 1.00 | NR1H2 (0.36) | NR1H2NR1H3ESR1ESR2MAPK1 | |
| SCHEMBL31463487 | 0.80 | — | — | |
| SCHEMBL702684 | 0.79 | NR1H2 (0.36) | NR1H2NR1H3ESR1ESR2MAPK1 | |
| SCHEMBL707249 | 0.79 | NR1H2 (0.36) | NR1H2NR1H3ESR1ESR2MAPK1 | |
| SCHEMBL8380445 | 0.74 | ESR1 (0.34) | NR1H2NR1H3ESR1ESR2MAPK1 | |
| SCHEMBL20328588 | 0.72 | ESR1 (0.37) | NR1H2NR1H3ESR1ESR2MAPK1 | |
| SCHEMBL3526796 | 0.72 | ESR1 (0.37) | NR1H2NR1H3ESR1ESR2MAPK1 | |
| SCHEMBL29749402 | 0.72 | ESR1 (0.37) | NR1H2NR1H3ESR1ESR2MAPK1 | |
| SCHEMBL3888384 | 0.72 | ESR1 (0.37) | NR1H2NR1H3ESR1ESR2MAPK1 | |
| SCHEMBL1314801 | 0.72 | ESR1 (0.38) | NR1H2NR1H3ESR1ESR2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174841-A1 | Breakable Emulsifiers | HALLIBURTON ENERGY SERVICES, INC. (US) | 2023-06-08 | — | — | US | disclosed |
| CN-110483413-B | Process for the preparation of carbocyclic sugar derivatives | 百缮药业(苏州)有限公司 | 2023-02-28 | — | — | CN | disclosed |
| EP-4112604-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-1-((1S,4R,5S)-2-FLUORO-4,5-DIHIDROXY-3-HYDROXY-METHYL-CYCLOPENT-2-ENYL)-1H-PYRIMIDIN-2-ONE | Ocuphire Pharma, Inc. (US) | 2023-01-04 | — | — | EP | disclosed |
| CN-107474034-B | Process for the preparation of carbocyclic sugar derivatives | 瑞沙恩医药公司 | 2020-06-30 | — | — | CN | disclosed |
| CN-110483413-A | The method for being used to prepare carbocyclic ring sugar derivatives | REXAHN PHARMACEUTICALS INC | 2019-11-22 | — | — | CN | disclosed |
| US-10345701-B2 | Photoresist polymers, photoresist compositions, methods of forming patterns and methods of manufacturing semiconductor devices | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2019-07-09 | — | — | US | disclosed |
| EP-3246320-B1 | PROCESS FOR THE PREPARATION OF 4-AMINO-1-((1S,4R,5S)-2-FLUORO-4,5-DIHYDROXY-3- HYDROXYMETHYL-CYCLOPENT-2-ENYL)-1H-PYRIMIDIN-2-ONE | REXAHN PHARMACEUTICALS INC (US) | 2019-05-08 | — | — | EP | disclosed |
| EP-3378855-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-1-((1S,4R,5S)-2-FLUORO-4,5-DIHIDROXY-3-HYDROXY-METHYL-CYCLOPENT-2-ENYL)-1H-PYRIMIDIN-2-ONE | Rexahn Pharmaceuticals, Inc. (US) | 2018-09-26 | — | — | EP | disclosed |
| EP-2970147-B1 | PROCESS FOR THE PREPARATION OF 4-AMINO-1-((1S,4R, 5S)-2-FLUORO-4,5-DIHYDROXY-3-HYDROXYMETHYL-CYCLOPENT-2-ENYL)-1H-PYRIMIDIN-2-ONE | REXAHN PHARMACEUTICALS INC (US) | 2018-05-30 | — | — | EP | disclosed |
| US-9920016-B2 | Process for the preparation of 4-amino 1-((1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-hydroxymethyl-cyclopent-2-enyl)-1H-pyrimidin-2-one | REXAHN PHARMACEUTICALS, INC. (US) | 2018-03-20 | — | — | US | disclosed |
| US-20150376142-A1 | Process for the Preparation of 4-Amino-1-((1S,4R,5S)-2-Fluoro-4,5-Dihydroxy-3-Hydroxymethyl-Cyclopent-2-Enyl)-1H-Pyrimidin-2-One | Ocuphire Pharma, Inc. | 2015-12-31 | — | — | US | disclosed |
| US-9150520-B2 | Process for the preparation of 4-amino-1-((1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-hydroxymethyl-cyclopent-2-enyl)-1H-pyrimidin-2-one | REXAHN PHARMACEUTICALS, INC. (US) | 2015-10-06 | — | — | US | disclosed |
| US-20140275537-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-1-((1S,4R,5S)-2-FLUORO-4,5-DIHYDROXY-3-HYDROXYMETHYL-CYCLOPENT-2-ENYL)-1H-PYRIMIDIN-2-ONE | REXAHN PHARMACEUTICALS, INC. (US) | 2014-09-18 | — | — | US | disclosed |
| US-8124239-B2 | Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same | FUJITSU LIMITED (JP) | 2012-02-28 | — | — | US | disclosed |
| US-20100155121-A1 | SILICA FILM FORMING MATERIAL, SILICA FILM AND METHOD OF MANUFACTURING THE SAME, MULTILAYER WIRING STRUCTURE AND METHOD OF MANUFACTURING THE SAME, AND SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME | FUJITSU LIMITED (JP) | 2010-06-24 | — | — | US | disclosed |
| US-7659357-B2 | Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed | FUJITSU LIMITED (JP) | 2010-02-09 | — | — | US | disclosed |
| US-20070026689-A1 | Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same | FUJITSU LIMITED (JP) | 2007-02-01 | — | — | US | disclosed |
| US-6811822-B2 | Method of waterproofing the surface of a polymer work piece | Institut fur Mikrotechnik Mainz (DE) | 2004-11-02 | — | — | US | disclosed |
| US-20030185992-A1 | Method of waterproofing the surface of a polymer work piece | INSTITUT FUR MIKROTECHNIK MAINZ GMBH (DE) | 2003-10-02 | — | — | US | disclosed |
| US-4851417-A | 9-substituted 6H-pyrido[4,3-b]carbazoles | RENSSELAER POLYTECHNIC INSTITUTE (US) | 1989-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376142-A1 | Process for the Preparation of 4-Amino-1-((1S,4R,5S)-2-Fluoro-4,5-Dihydroxy-3-Hydroxymethyl-Cyclopent-2-Enyl)-1H-Pyrimidin-2-One | RXFP4, RXFP1, NPY4R | NR1H2 2093/4885NR1H3 1691/4885ESR1 2223/4885 |
| US-20140275537-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-1-((1S,4R,5S)-2-FLUORO-4,5-DIHYDROXY-3-HYDROXYMETHYL-CYCLOPENT-2-ENYL)-1H-PYRIMIDIN-2-ONE | RXFP4, RXFP1, NPY4R | NR1H2 1913/4885NR1H3 1534/4885ESR1 2069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.