SCHEMBL8380445

SCHEMBL8380445

[Li][Si](c1ccccc1)(c1ccccc1)C(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.34
ESR2 Q92731 3/20 0.34
MAPK1 P28482 1/20 0.33
NR1H2 P55055 2/20 0.32
NR1H3 Q13133 2/20 0.32
ALDH1A1 P00352 3/20 0.31
TAAR1 Q96RJ0 2/20 0.31
ALOX15 P16050 1/20 0.31
SLC6A2 P23975 1/20 0.31
LMNA P02545 2/20 0.31
ATM Q13315 2/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
BLM P54132 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TSHR P16473 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL704604 0.74 NR1H2 (0.36) ESR1ESR2MAPK1NR1H2NR1H3
SCHEMBL13933322 0.74 NR1H2 (0.36) ESR1ESR2MAPK1NR1H2NR1H3
SCHEMBL3526796 0.72 ESR1 (0.37) ESR1ESR2MAPK1NR1H2NR1H3
SCHEMBL29749402 0.72 ESR1 (0.37) ESR1ESR2MAPK1NR1H2NR1H3
SCHEMBL3888384 0.72 ESR1 (0.37) ESR1ESR2MAPK1NR1H2NR1H3
SCHEMBL20328588 0.72 ESR1 (0.37) ESR1ESR2MAPK1NR1H2NR1H3
SCHEMBL841941 0.72 TAAR1 (0.34) ESR1ESR2MAPK1NR1H2NR1H3
SCHEMBL8381381 0.70 TAAR1 (0.37) ESR1ESR2MAPK1NR1H2NR1H3
SCHEMBL6013056 0.70 ESR1 (0.41) ESR1ESR2MAPK1NR1H2NR1H3
SCHEMBL15889153 0.70 ESR1 (0.41) ESR1ESR2MAPK1NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0630933-B1 A method of producing a semiconducting material NIPPON OIL CO LTD (JP) 1999-04-14 EP disclosed
US-5700400-A Method for producing a semiconducting material NIPPON OIL CO., LTD. (JP) 1997-12-23 US disclosed
EP-0551771-B1 Process for producing polysilanes NIPPON OIL CO LTD (JP) 1997-07-30 EP disclosed
US-5620531-A Photovoltaic element NIPPON OIL CO., LTD. (JP) 1997-04-15 US disclosed
EP-0717451-A2 Photovoltaic element NIPPON OIL CO., LTD. (JP) 1996-06-19 EP disclosed
EP-0630933-A2 A method of producing a semiconducting material NIPPON OIL CO. LTD. (JP) 1994-12-28 EP disclosed
US-5304622-A Process for producing polysilanes NIPPON OIL COMPANY, LTD. (JP) 1994-04-19 US disclosed
EP-0551771-A2 Process for producing polysilanes NIPPON OIL CO. LTD. (JP) 1993-07-21 EP disclosed