Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.55 |
| ▸ | CNR2 | P34972 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7041235 | 0.92 | CNR1 (0.55) | CNR1CNR2ALOX15KDM4EALDH1A1 | |
| SCHEMBL7041732 | 0.82 | CNR1 (0.58) | CNR1CNR2ALOX15 | |
| SCHEMBL7041750 | 0.81 | CNR1 (0.44) | CNR1CNR2KDM4EALDH1A1TSHR | |
| SCHEMBL4080283 | 0.80 | CNR1 (0.58) | CNR1CNR2ALOX15KDM4EALDH1A1 | |
| SCHEMBL7044617 | 0.79 | GABRA2 (0.47) | ALOX15TSHRHSD17B10 | |
| SCHEMBL7043236 | 0.78 | CNR1 (0.64) | CNR1 | |
| SCHEMBL7046420 | 0.76 | CNR1 (0.64) | CNR1CNR2 | |
| SCHEMBL7046457 | 0.75 | ALOX15 (0.48) | CNR1ALOX15HPGD | |
| SCHEMBL7044437 | 0.74 | CNR1 (0.55) | CNR1CNR2ALOX15 | |
| SCHEMBL7045705 | 0.72 | GABRA2 (0.46) | ALOX15TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | claimed |
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |