Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 6/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7044617 | 0.92 | GABRA2 (0.47) | GABRA2GABRB2SIRT2SIRT1SIRT3 | |
| SCHEMBL7041804 | 0.81 | ALOX15 (0.47) | GABRA2GABRB2ALOX15MAPTGAA | |
| SCHEMBL7041235 | 0.78 | CNR1 (0.55) | ALOX15TSHRHSD17B10 | |
| SCHEMBL6553466 | 0.77 | ALOX5 (0.51) | GABRA2GABRB2SIRT2SIRT1SIRT3 | |
| SCHEMBL7044707 | 0.74 | ALOX5 (0.52) | GABRA2GABRB2ALOX15MAPTNPC1 | |
| SCHEMBL7044693 | 0.74 | CNR1 (0.64) | — | |
| SCHEMBL7048167 | 0.74 | CNR1 (0.64) | — | |
| SCHEMBL7041750 | 0.73 | CNR1 (0.44) | ALPLNPC1TSHR | |
| SCHEMBL7046402 | 0.72 | CNR1 (0.55) | ALOX15TSHRHSD17B10 | |
| SCHEMBL1149801 | 0.69 | DAO (0.48) | GABRA2GABRB2ALPLALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |