Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048218 | 0.90 | — | — | |
| SCHEMBL7046399 | 0.89 | CNR1 (0.51) | KDM4EALDH1A1CYP1A2CYP3A4HPGD | |
| SCHEMBL7044567 | 0.88 | CSNK2A2 (0.47) | — | |
| SCHEMBL7046656 | 0.87 | CNR1 (0.52) | KDM4EALDH1A1CYP1A2CYP3A4HPGD | |
| SCHEMBL7044710 | 0.80 | KDM4E (0.43) | KDM4EALDH1A1HPGDSMN1; SMN2CNR1 | |
| SCHEMBL7041234 | 0.77 | CNR1 (0.48) | KDM4EALDH1A1CYP1A2CYP3A4HPGD | |
| SCHEMBL7046157 | 0.76 | CNR1 (0.49) | CNR1GCGR | |
| SCHEMBL5268736 | 0.72 | CNR1 (0.58) | KDM4EALDH1A1HPGDCNR1GCGR | |
| SCHEMBL7043396 | 0.71 | CNR1 (0.61) | ALDH1A1HPGDCNR1 | |
| SCHEMBL7046592 | 0.71 | CNR1 (0.61) | CNR1GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | claimed |
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |