Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042652 | 0.79 | ALDH1A1 (0.42) | CNR1PTGS2MAPK13MAPK12MAPK11 | |
| SCHEMBL7043396 | 0.79 | CNR1 (0.61) | CNR1PTGS1PTGS2 | |
| SCHEMBL7044568 | 0.79 | CNR1 (0.48) | CNR1CNR2 | |
| SCHEMBL7046182 | 0.78 | PIN1 (0.42) | — | |
| SCHEMBL7046157 | 0.77 | CNR1 (0.49) | CNR1PTGS1PTGS2MAPK13GCGR | |
| SCHEMBL4076039 | 0.76 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL5268736 | 0.72 | CNR1 (0.58) | CNR1PTGS1PTGS2MAPK13GCGR | |
| SCHEMBL7046455 | 0.71 | KDM4E (0.46) | CNR1GCGR | |
| SCHEMBL4076020 | 0.69 | CNR1 (1.00) | CNR1 | |
| SCHEMBL7044620 | 0.69 | KDM4E (0.49) | CNR1MAPK13GCGRMAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |